Assessment of fatigue and autonomic dysfunction in myasthenia gravis – case report
Introduction: Myasthenia gravis (MG) is an autoimmune disease in which neuromuscular conduction disorders occur. The reason is the loss of acetylcholine receptors and the presence of antibodies directed against these receptors. The most characteristic symptoms of myasthenia gravis are: tenderness an...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2019-05-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/26103 |
| _version_ | 1811303384085430272 |
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| author | Klaudia Kwiatkowska Martyna Lamtych Karolina Kubiak Ewelina Litwa Nataliia Badiuk |
| author_facet | Klaudia Kwiatkowska Martyna Lamtych Karolina Kubiak Ewelina Litwa Nataliia Badiuk |
| author_sort | Klaudia Kwiatkowska |
| collection | DOAJ |
| description | Introduction: Myasthenia gravis (MG) is an autoimmune disease in which neuromuscular conduction disorders occur. The reason is the loss of acetylcholine receptors and the presence of antibodies directed against these receptors. The most characteristic symptoms of myasthenia gravis are: tenderness and weakness of striated muscles, which intensify particularly during exercise and in the evening. Non-motor symptoms such as: fatigue, disorders of the autonomic nervous system can be asymptomatic, and in a significant proportion of cases significantly affect the quality of life. A full understanding of non-motors symptoms is needed to treat patients with MG. The aim of the study was to present the characteristics of non-motor symptoms on the example of a patient with myasthenia gravis.
Material and methods: A 50-year-old woman who had been suffering from myasthenia gravis for 23 years was examined. Chalder Fatigue Scale, Epworth Sleepiness Scale, Orthostatic Grading Scale were used to evaluate non-motor symptoms. The orthostatic reaction was tested using the tilt test.
Results: The most frequently reported non-motors symptoms in the patient were: chronic fatigue, sleep disturbances and cardiovascular symptoms (orthostatic intolerance, weakness).
Conclusions: Myasthenia gravis is characterized by a large variability of symptoms. An important part of the clinical picture are non-motor symptoms that can affect the functioning of patients in everyday life. |
| first_indexed | 2024-04-13T07:47:01Z |
| format | Article |
| id | doaj.art-9a68c3d10d21432f9cf1a9398c1ecf74 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-13T07:47:01Z |
| publishDate | 2019-05-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-9a68c3d10d21432f9cf1a9398c1ecf742022-12-22T02:55:40ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062019-05-0195Assessment of fatigue and autonomic dysfunction in myasthenia gravis – case reportKlaudia Kwiatkowska0Martyna Lamtych1Karolina Kubiak2Ewelina Litwa3Nataliia Badiuk4Student Scientific Circle at Chair of Hygiene, Epidemiology and Ergonomics, Faculty of Health Sciences, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz,Student Scientific Circle at Chair of Hygiene, Epidemiology and Ergonomics, Faculty of Health Sciences, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz,Student Scientific Circle at Chair of Hygiene, Epidemiology and Ergonomics, Faculty of Health Sciences, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz,Scientific Circle at Department of Hygiene, Epidemiology and Ergonomics. Division of Ergonomics and Exercise Physiology, Nicolaus Copernicus University in Toruń, Collegium Medicum in BydgoszczState Enterprise Ukrainian Research Institute for Medicine of Transport, Ministry of Health of Ukraine, OdesaIntroduction: Myasthenia gravis (MG) is an autoimmune disease in which neuromuscular conduction disorders occur. The reason is the loss of acetylcholine receptors and the presence of antibodies directed against these receptors. The most characteristic symptoms of myasthenia gravis are: tenderness and weakness of striated muscles, which intensify particularly during exercise and in the evening. Non-motor symptoms such as: fatigue, disorders of the autonomic nervous system can be asymptomatic, and in a significant proportion of cases significantly affect the quality of life. A full understanding of non-motors symptoms is needed to treat patients with MG. The aim of the study was to present the characteristics of non-motor symptoms on the example of a patient with myasthenia gravis. Material and methods: A 50-year-old woman who had been suffering from myasthenia gravis for 23 years was examined. Chalder Fatigue Scale, Epworth Sleepiness Scale, Orthostatic Grading Scale were used to evaluate non-motor symptoms. The orthostatic reaction was tested using the tilt test. Results: The most frequently reported non-motors symptoms in the patient were: chronic fatigue, sleep disturbances and cardiovascular symptoms (orthostatic intolerance, weakness). Conclusions: Myasthenia gravis is characterized by a large variability of symptoms. An important part of the clinical picture are non-motor symptoms that can affect the functioning of patients in everyday life.https://apcz.umk.pl/JEHS/article/view/26103myasthenia gravisnon-motor symptomsfatigue |
| spellingShingle | Klaudia Kwiatkowska Martyna Lamtych Karolina Kubiak Ewelina Litwa Nataliia Badiuk Assessment of fatigue and autonomic dysfunction in myasthenia gravis – case report Journal of Education, Health and Sport myasthenia gravis non-motor symptoms fatigue |
| title | Assessment of fatigue and autonomic dysfunction in myasthenia gravis – case report |
| title_full | Assessment of fatigue and autonomic dysfunction in myasthenia gravis – case report |
| title_fullStr | Assessment of fatigue and autonomic dysfunction in myasthenia gravis – case report |
| title_full_unstemmed | Assessment of fatigue and autonomic dysfunction in myasthenia gravis – case report |
| title_short | Assessment of fatigue and autonomic dysfunction in myasthenia gravis – case report |
| title_sort | assessment of fatigue and autonomic dysfunction in myasthenia gravis case report |
| topic | myasthenia gravis non-motor symptoms fatigue |
| url | https://apcz.umk.pl/JEHS/article/view/26103 |
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