No impact of helminth coinfection in patients with smear positive tuberculosis on immunoglobulin levels using a novel method measuring Mycobacterium tuberculosis-specific antibodies

No impact of helminth coinfection in patients with smear positive tuberculosis on immunoglobulin levels using a novel method measuring Mycobacterium tuberculosis-specific antibodies

Abstract Helminth/tuberculosis (TB)-coinfection can reduce cell-mediated immunity against Mycobacterium tuberculosis (Mtb) and increase disease severity, although the effects are highly helminth species dependent. Mtb have long been ranked as the number one single infectious agent claiming the most...

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Bibliographic Details
Main Authors: Giggil Pushpamithran, Camilla Skoglund, Fanny Olsson, Melissa Méndez-Aranda, Thomas Schön, Mårten Segelmark, Olle Stendahl, Robert H. Gilman, Robert Blomgran
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Mycobacterium tuberculosis
Active pulmonary TB
Helminth coinfection
Adaptive humoral immune response
Mtb-specific IgG IgA IgM
Online Access:https://doi.org/10.1186/s13223-023-00808-0

Internet

https://doi.org/10.1186/s13223-023-00808-0

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