Supramolecular chemistry at interfaces: host-guest interactions for attaching PEG and 5-fluorouracil to the surface of porous nanosilica

Supramolecular chemistry at interfaces: host-guest interactions for attaching PEG and 5-fluorouracil to the surface of porous nanosilica

Porous nanosilica (PNS) has been attracting much attention in fabrication of nanocarriers for a drug delivery system (DDS). However, the unmodified PNS-based carriers exhibited a significant initial burst release of drug, which may limit their potential clinical application. In this study, PNS was s...

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Bibliographic Details
Main Authors: Tran Tuong Vi, Vo Uyen Vy, Pham Dong Yen, Tran Dai Lam, Nguyen Thi Hiep, Tran Ngoc Quyen, Nguyen Cuu Khoa, Thu Le Van, Nguyen Dai Hai
Format: Article
Language:English
Published: De Gruyter 2016-12-01
Series:Green Processing and Synthesis
Subjects:
5-fluorouracil
cancer therapy
drug delivery systems
porous nanosilica
Online Access:https://doi.org/10.1515/gps-2016-0049

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