Atrial fibrillation: Primary prevention, secondary prevention, and prevention of thromboembolic complications: Part 2
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, once thought to be benign as long as the ventricular rate was controlled, is associated with significant cardiac morbidity and mortality. Increasing life expectancy driven by improved health care and decreased fertility rates ha...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1060096/full |
| _version_ | 1811155443390611456 |
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| author | Richard G. Trohman Henry D. Huang Parikshit S. Sharma |
| author_facet | Richard G. Trohman Henry D. Huang Parikshit S. Sharma |
| author_sort | Richard G. Trohman |
| collection | DOAJ |
| description | Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, once thought to be benign as long as the ventricular rate was controlled, is associated with significant cardiac morbidity and mortality. Increasing life expectancy driven by improved health care and decreased fertility rates has, in most of the world, resulted in the population aged ≥65 years growing more rapidly than the overall population. As the population ages, projections suggest that the burden of AF may increase more than 60% by 2050. Although considerable progress has been made in the treatment and management of AF, primary prevention, secondary prevention, and prevention of thromboembolic complications remain a work in progress. This narrative review was facilitated by a search of MEDLINE to identify peer-reviewed clinical trials, randomized controlled trials, meta-analyses, and other clinically relevant studies. The search was limited to English-language reports published between 1950 and 2021. Atrial fibrillation was searched using the terms primary prevention, hyperthyroidism, Wolff-Parkinson-White syndrome, catheter ablation, surgical ablation, hybrid ablation, stroke prevention, anticoagulation, left atrial occlusion and atrial excision. Google and Google scholar as well as bibliographies of identified articles were reviewed for additional references. In these two manuscripts, we discuss the current strategies available to prevent AF, then compare non-invasive and invasive treatment strategies to diminish AF recurrence. In addition, we examine the pharmacological, percutaneous device and surgical approaches to prevent stroke as well as other types of thromboembolic events. |
| first_indexed | 2024-04-10T04:34:05Z |
| format | Article |
| id | doaj.art-9a6ef9e72c014800bfa40f997df39ebd |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-10T04:34:05Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-9a6ef9e72c014800bfa40f997df39ebd2023-03-10T05:23:41ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-03-01910.3389/fcvm.2022.10600961060096Atrial fibrillation: Primary prevention, secondary prevention, and prevention of thromboembolic complications: Part 2Richard G. TrohmanHenry D. HuangParikshit S. SharmaAtrial fibrillation (AF), the most common sustained cardiac arrhythmia, once thought to be benign as long as the ventricular rate was controlled, is associated with significant cardiac morbidity and mortality. Increasing life expectancy driven by improved health care and decreased fertility rates has, in most of the world, resulted in the population aged ≥65 years growing more rapidly than the overall population. As the population ages, projections suggest that the burden of AF may increase more than 60% by 2050. Although considerable progress has been made in the treatment and management of AF, primary prevention, secondary prevention, and prevention of thromboembolic complications remain a work in progress. This narrative review was facilitated by a search of MEDLINE to identify peer-reviewed clinical trials, randomized controlled trials, meta-analyses, and other clinically relevant studies. The search was limited to English-language reports published between 1950 and 2021. Atrial fibrillation was searched using the terms primary prevention, hyperthyroidism, Wolff-Parkinson-White syndrome, catheter ablation, surgical ablation, hybrid ablation, stroke prevention, anticoagulation, left atrial occlusion and atrial excision. Google and Google scholar as well as bibliographies of identified articles were reviewed for additional references. In these two manuscripts, we discuss the current strategies available to prevent AF, then compare non-invasive and invasive treatment strategies to diminish AF recurrence. In addition, we examine the pharmacological, percutaneous device and surgical approaches to prevent stroke as well as other types of thromboembolic events.https://www.frontiersin.org/articles/10.3389/fcvm.2022.1060096/fullpathophysiologyepidemiologydietlifestyle modificationpharmacological interventionscatheter ablation |
| spellingShingle | Richard G. Trohman Henry D. Huang Parikshit S. Sharma Atrial fibrillation: Primary prevention, secondary prevention, and prevention of thromboembolic complications: Part 2 Frontiers in Cardiovascular Medicine pathophysiology epidemiology diet lifestyle modification pharmacological interventions catheter ablation |
| title | Atrial fibrillation: Primary prevention, secondary prevention, and prevention of thromboembolic complications: Part 2 |
| title_full | Atrial fibrillation: Primary prevention, secondary prevention, and prevention of thromboembolic complications: Part 2 |
| title_fullStr | Atrial fibrillation: Primary prevention, secondary prevention, and prevention of thromboembolic complications: Part 2 |
| title_full_unstemmed | Atrial fibrillation: Primary prevention, secondary prevention, and prevention of thromboembolic complications: Part 2 |
| title_short | Atrial fibrillation: Primary prevention, secondary prevention, and prevention of thromboembolic complications: Part 2 |
| title_sort | atrial fibrillation primary prevention secondary prevention and prevention of thromboembolic complications part 2 |
| topic | pathophysiology epidemiology diet lifestyle modification pharmacological interventions catheter ablation |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1060096/full |
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