Industrial Production of Proteins with <i>Pichia pastoris</i>—<i>Komagataella phaffii</i>

Industrial Production of Proteins with <i>Pichia pastoris</i>—<i>Komagataella phaffii</i>

Since the mid-1960s, methylotrophic yeast <i>Komagataella phaffii</i> (previously described as <i>Pichia pastoris</i>) has received increasing scientific attention. The interest for the industrial production of proteins for different applications (e.g., feed, food additives,...

Full description

Bibliographic Details
Main Authors:	Giovanni Davide Barone, Anita Emmerstorfer-Augustin, Antonino Biundo, Isabella Pisano, Paola Coccetti, Valeria Mapelli, Andrea Camattari
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	Biomolecules
Subjects:	<i>Pichia pastoris</i> <i>Komagataella phaffii</i> methylotrophic yeast protein production biotechnology applied biotechnology
Online Access:	https://www.mdpi.com/2218-273X/13/3/441

Similar Items

Role of Dissimilative Pathway of <i>Komagataella phaffii</i> (<i>Pichia pastoris</i>): Formaldehyde Toxicity and Energy Metabolism
by: Julio Berrios, et al.
Published: (2022-07-01)

Advances in <i>Komagataella phaffii</i> Engineering for the Production of Renewable Chemicals and Proteins
by: Clara Vida Galrão Corrêa Carneiro, et al.
Published: (2022-10-01)

Evaluation of reference genes for transcript analyses in Komagataella phaffii (Pichia pastoris)
by: Mihail Besleaga, et al.
Published: (2023-03-01)

<i>Pichia pastoris</i> (<i>Komagataella phaffii</i>) as a Cost-Effective Tool for Vaccine Production for Low- and Middle-Income Countries (LMICs)
by: Salomé de Sá Magalhães, et al.
Published: (2021-08-01)

Advances in Cell Engineering of the <i>Komagataella phaffii</i> Platform for Recombinant Protein Production
by: Cristina Bustos, et al.
Published: (2022-04-01)

Depletion of Boric Acid and Cobalt from Cultivation Media: Impact on Recombinant Protein Production with <i>Komagataella phaffii</i>
by: Alexander Pekarsky, et al.
Published: (2020-12-01)

Effect of Methionine on Gene Expression in <i>Komagataella phaffii</i> Cells
by: Tatiana Ianshina, et al.
Published: (2023-03-01)

<i>Komagataella phaffii</i> Cue5 Piggybacks on Lipid Droplets for Its Vacuolar Degradation during Stationary Phase Lipophagy
by: Ravinder Kumar, et al.
Published: (2022-01-01)

Transcriptome Analysis Unveils the Effects of Proline on Gene Expression in the Yeast <i>Komagataella phaffii</i>
by: Andrey Rumyantsev, et al.
Published: (2021-12-01)

Tuning Fatty Acid Profile and Yield in <i>Pichia pastoris</i>
by: Simon Kobalter, et al.
Published: (2023-12-01)

Alternative PCR-Based Approaches for Generation of <i>Komagataella phaffii</i> Strains
by: Anastasiya Makeeva, et al.
Published: (2023-09-01)

Comparison of CRISPR-MAD7 and CRISPR-Cas9 for Gene Disruptions in <i>Komagataella phaffii</i>
by: Kirill Smirnov, et al.
Published: (2024-03-01)

PAOX1 expression in mixed-substrate continuous cultures of Komagataella phaffii (Pichia pastoris) is completely determined by methanol consumption regardless of the secondary carbon source
by: Anamika Singh, et al.
Published: (2023-04-01)

Orthologous promoters from related methylotrophic yeasts surpass expression of endogenous promoters of Pichia pastoris
by: Thomas Vogl, et al.
Published: (2020-02-01)

Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid
by: Sílvia Àvila-Cabré, et al.
Published: (2023-11-01)

Development and validation of promoter prediction system for recombinant lipase expression in Pichia pastoris
by: Gogo, Mayaki Fatima
Published: (2017)

Biovalorization of Lignocellulosic Materials for Xylitol Production by the Yeast <i>Komagataella pastoris</i>
by: Diana Araújo, et al.
Published: (2021-06-01)

Human Sterols Are Overproduced, Stored and Excreted in Yeasts
by: Astrid Radkohl, et al.
Published: (2024-01-01)

Glycogen Granules Are Degraded by Non-Selective Autophagy in Nitrogen-Starved <i>Komagataella phaffii</i>
by: Nimna V. Wijewantha, et al.
Published: (2024-03-01)

Scalable protein production by Komagataella phaffii enabled by ARS plasmids and carbon source-based selection
by: Florian Weiss, et al.
Published: (2024-04-01)

Heterologous Expression of Extracellular Proteinase pAsPs of <i>Aspergillus pseudotamarii</i> in <i>Komagataella phaffii</i>
by: Andrey Valentinovich Zadorozhny, et al.
Published: (2022-11-01)

Production of a Recombinant Non-Hydroxylated Gelatin Mimetic in <i>Pichia pastoris</i> for Biomedical Applications
by: Pia Gellermann, et al.
Published: (2019-09-01)

L-Asparaginase from <i>Penicillium sizovae</i> Produced by a Recombinant <i>Komagataella phaffii</i> Strain
by: Marcela Freitas, et al.
Published: (2022-06-01)

Diversity and occurrence of methylotrophic yeasts used in genetic engineering
by: A. S. Rozanov, et al.
Published: (2020-04-01)

Constitutive Expression in <i>Komagataella phaffii</i> of Mature <i>Rhizopus oryzae</i> Lipase Jointly with Its Truncated Prosequence Improves Production and the Biocatalyst Operational Stability
by: Josu López-Fernández, et al.
Published: (2021-09-01)

<i>Komagataella phaffii</i> as a Platform for Heterologous Expression of Enzymes Used for Industry
by: Tamara M. Khlebodarova, et al.
Published: (2024-02-01)

Constitutive High Expression Level of a Synthetic Deleted Encoding Gene of <i>Talaromyces minioluteus</i> Endodextranase Variant (<i>r</i>–<i>Tm</i>DEX49A–ΔSP–ΔN30) in <i>Komagataella phaffii</i> (<i>Pichia pastoris</i>)
by: Roberto Carlos Arísticas Ribalta, et al.
Published: (2022-07-01)

Optimisation of Recombinant Myrosinase Production in <i>Pichia pastoris</i>
by: Zuzana Rosenbergová, et al.
Published: (2021-04-01)

Nitrogen Starvation and Stationary Phase Lipophagy Have Distinct Molecular Mechanisms
by: Ravinder Kumar, et al.
Published: (2020-11-01)

Second generation Pichia pastoris strain and bioprocess designs
by: Burcu Gündüz Ergün, et al.
Published: (2022-12-01)

Improved Production of Recombinant Myrosinase in <i>Pichia pastoris</i>
by: Zuzana Rosenbergová, et al.
Published: (2021-11-01)

Engineering Komagataella phaffii to biosynthesize cordycepin from methanol which drives global metabolic alterations at the transcription level
by: Huiping Tan, et al.
Published: (2023-06-01)

Expression and Characterization of an Alginate Lyase and Its Thermostable Mutant in <i>Pichia pastoris</i>
by: Suxiao Yang, et al.
Published: (2020-06-01)

Production and Characterisation of Stabilised PV-3 Virus-like Particles Using <i>Pichia pastoris</i>
by: Lee Sherry, et al.
Published: (2022-09-01)

Expression of <i>Pleurotus ostreatus</i> Laccase Gene in <i>Pichia pastoris</i> and Its Degradation of Corn Stover Lignin
by: Qian Song, et al.
Published: (2020-04-01)

High throughput 13C-metabolic flux analysis of 3-hydroxypropionic acid producing Pichia pastoris reveals limited availability of acetyl-CoA and ATP due to tight control of the glycolytic flux
by: Albert Fina, et al.
Published: (2023-06-01)

Клонирование и экспрессия гена маннаназы Thermothielavioides terrestris в Komagataella phaffii
by: Задорожный А.B., et al.
Published: (2022-12-01)

Effects of Temperature and pH on Recombinant Thaumatin II Production by <i>Pichia pastoris</i>
by: Jewel Ann Joseph, et al.
Published: (2022-05-01)

Performance of Recombinant <i>Komagataella phaffii</i> in Plant-Based Meat Flavor Compound-Leghemoglobin (LegH) Production through Fed-Batch Fermentations
by: Arturs Suleiko, et al.
Published: (2024-01-01)

Enhanced Expression of Alcohol Dehydrogenase I in <i>Pichia pastoris</i> Reduces the Content of Acetaldehyde in Wines
by: Kun Geng, et al.
Published: (2023-12-01)