Quality assuring “Plan of the day” selection in a multicentre adaptive bladder trial: Implementation of a pre-accrual IGRT guidance and assessment module
Background and purpose: Hypofractionated bladder RT with or without image guided adaptive planning (HYBRID) is a multicentre clinical trial investigating “Plan of the Day” (PoD) adaptive radiotherapy for bladder cancer. To ensure correct PoD selection a pre-accrual guidance and assessment module was...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-11-01
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| Series: | Clinical and Translational Radiation Oncology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405630819300023 |
| _version_ | 1818672967823917056 |
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| author | Emma Patel Yat Tsang Angela Baker Jenny Callender Shaista Hafeez Emma Hall Vibeke Nordmark Hansen Rebecca Lewis Helen McNair Elizabeth Miles Robert Huddart |
| author_facet | Emma Patel Yat Tsang Angela Baker Jenny Callender Shaista Hafeez Emma Hall Vibeke Nordmark Hansen Rebecca Lewis Helen McNair Elizabeth Miles Robert Huddart |
| author_sort | Emma Patel |
| collection | DOAJ |
| description | Background and purpose: Hypofractionated bladder RT with or without image guided adaptive planning (HYBRID) is a multicentre clinical trial investigating “Plan of the Day” (PoD) adaptive radiotherapy for bladder cancer. To ensure correct PoD selection a pre-accrual guidance and assessment module was developed as part of an image guided radiotherapy quality assurance (IGRT QA) credentialing programme. This study aimed to evaluate its feasibility and effectiveness across multiple recruiting centres. Materials and methods: Individuals from participating centres remotely accessed an image database in order to complete the PoD module. An assessment score of ≥83% was required in order to receive QA approval. A questionnaire was used to gather user feedback on the module. PoD decisions for the first patient at each recruiting centre were retrospectively reviewed for protocol adherence. Results: 71 radiation therapists (RTTs) from 10 centres completed the PoD module. The median assessment score was 92% (Range: 58–100%) with 79% of RTTs passing the assessment on first attempt. All questionnaire respondents reported that the PoD module prepared them for plan selection. In 51/60 of on-trial treatments reviewed, the PoD selected by the centre agreed with QA reviewers. Conclusions: The PoD QA module was successfully implemented in a multicentre trial and enabled pre-accrual assessment of protocol understanding. This increased operator confidence and resulted in appropriate PoD selection on-trial. Keywords: IGRT, Adaptive, Bladder, Radiotherapy, Trial QA |
| first_indexed | 2024-12-17T07:48:19Z |
| format | Article |
| id | doaj.art-9a71aebad6584338922ccab287ba8b16 |
| institution | Directory Open Access Journal |
| issn | 2405-6308 |
| language | English |
| last_indexed | 2024-12-17T07:48:19Z |
| publishDate | 2019-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical and Translational Radiation Oncology |
| spelling | doaj.art-9a71aebad6584338922ccab287ba8b162022-12-21T21:57:55ZengElsevierClinical and Translational Radiation Oncology2405-63082019-11-01192732Quality assuring “Plan of the day” selection in a multicentre adaptive bladder trial: Implementation of a pre-accrual IGRT guidance and assessment moduleEmma Patel0Yat Tsang1Angela Baker2Jenny Callender3Shaista Hafeez4Emma Hall5Vibeke Nordmark Hansen6Rebecca Lewis7Helen McNair8Elizabeth Miles9Robert Huddart10Radiotherapy Physics Department, University College London Hospitals NHS Foundation Trust, London, United KingdomNational Radiotherapy Trials Quality Assurance Group, Mount Vernon Hospital, Northwood, United Kingdom; Corresponding author at: National Radiotherapy Trials Quality Assurance Group, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood HA6 2RN, United Kingdom.Oxford University Hospitals NHS Foundation Trust, Oxford, United KingdomUniversity of Liverpool, Liverpool, United KingdomDepartment of Radiotherapy and Imaging, The Institute of Cancer Research & The Royal Marsden NHS Foundation Trust, London, United KingdomClinical Trials and Statistics Unit, The Institute of Cancer Research, London, United KingdomDepartment of Radiotherapy and Imaging, The Institute of Cancer Research & The Royal Marsden NHS Foundation Trust, London, United KingdomClinical Trials and Statistics Unit, The Institute of Cancer Research, London, United KingdomDepartment of Radiotherapy and Imaging, The Institute of Cancer Research & The Royal Marsden NHS Foundation Trust, London, United KingdomNational Radiotherapy Trials Quality Assurance Group, Mount Vernon Hospital, Northwood, United KingdomDepartment of Radiotherapy and Imaging, The Institute of Cancer Research & The Royal Marsden NHS Foundation Trust, London, United KingdomBackground and purpose: Hypofractionated bladder RT with or without image guided adaptive planning (HYBRID) is a multicentre clinical trial investigating “Plan of the Day” (PoD) adaptive radiotherapy for bladder cancer. To ensure correct PoD selection a pre-accrual guidance and assessment module was developed as part of an image guided radiotherapy quality assurance (IGRT QA) credentialing programme. This study aimed to evaluate its feasibility and effectiveness across multiple recruiting centres. Materials and methods: Individuals from participating centres remotely accessed an image database in order to complete the PoD module. An assessment score of ≥83% was required in order to receive QA approval. A questionnaire was used to gather user feedback on the module. PoD decisions for the first patient at each recruiting centre were retrospectively reviewed for protocol adherence. Results: 71 radiation therapists (RTTs) from 10 centres completed the PoD module. The median assessment score was 92% (Range: 58–100%) with 79% of RTTs passing the assessment on first attempt. All questionnaire respondents reported that the PoD module prepared them for plan selection. In 51/60 of on-trial treatments reviewed, the PoD selected by the centre agreed with QA reviewers. Conclusions: The PoD QA module was successfully implemented in a multicentre trial and enabled pre-accrual assessment of protocol understanding. This increased operator confidence and resulted in appropriate PoD selection on-trial. Keywords: IGRT, Adaptive, Bladder, Radiotherapy, Trial QAhttp://www.sciencedirect.com/science/article/pii/S2405630819300023 |
| spellingShingle | Emma Patel Yat Tsang Angela Baker Jenny Callender Shaista Hafeez Emma Hall Vibeke Nordmark Hansen Rebecca Lewis Helen McNair Elizabeth Miles Robert Huddart Quality assuring “Plan of the day” selection in a multicentre adaptive bladder trial: Implementation of a pre-accrual IGRT guidance and assessment module Clinical and Translational Radiation Oncology |
| title | Quality assuring “Plan of the day” selection in a multicentre adaptive bladder trial: Implementation of a pre-accrual IGRT guidance and assessment module |
| title_full | Quality assuring “Plan of the day” selection in a multicentre adaptive bladder trial: Implementation of a pre-accrual IGRT guidance and assessment module |
| title_fullStr | Quality assuring “Plan of the day” selection in a multicentre adaptive bladder trial: Implementation of a pre-accrual IGRT guidance and assessment module |
| title_full_unstemmed | Quality assuring “Plan of the day” selection in a multicentre adaptive bladder trial: Implementation of a pre-accrual IGRT guidance and assessment module |
| title_short | Quality assuring “Plan of the day” selection in a multicentre adaptive bladder trial: Implementation of a pre-accrual IGRT guidance and assessment module |
| title_sort | quality assuring plan of the day selection in a multicentre adaptive bladder trial implementation of a pre accrual igrt guidance and assessment module |
| url | http://www.sciencedirect.com/science/article/pii/S2405630819300023 |
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