Efficient Lithium-Based Upconversion Nanoparticles for Single-Particle Imaging and Temperature Sensing
Upconversion Nanoparticles (UCNPs) have attracted exceptional attention due to their great potential in high-contrast, free-background biofluorescence deep tissue imaging and quantum sensing. Most of these interesting studies have been performed using an ensemble of UCNPs as fluorescent probes in bi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/16/12/4354 |
| _version_ | 1797593731901161472 |
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| author | Yahya A. Alzahrani Abdulaziz Alromaeh Masfer Alkahtani |
| author_facet | Yahya A. Alzahrani Abdulaziz Alromaeh Masfer Alkahtani |
| author_sort | Yahya A. Alzahrani |
| collection | DOAJ |
| description | Upconversion Nanoparticles (UCNPs) have attracted exceptional attention due to their great potential in high-contrast, free-background biofluorescence deep tissue imaging and quantum sensing. Most of these interesting studies have been performed using an ensemble of UCNPs as fluorescent probes in bioapplications. Here, we report a synthesis of small and efficient YLiF<sub>4</sub>:Yb,Er UCNPs for single-particle imaging as well as sensitive optical temperature sensing. The reported particles demonstrated a bright and photostable upconversion emission at a single particle level under a low laser intensity excitation of 20 W/cm<sup>2</sup>. Furthermore, the synthesized UCNPs were tested and compared to the commonly used two-photon excitation QDs and organic dyes and showed a nine times better performance at a single particle level under the same experimental conditions. In addition, the synthesized UCNPs demonstrated sensitive optical temperature sensing at a single particle level within the biological temperature range. The good optical properties of single YLiF<sub>4</sub>:Yb,Er UCNPs open an avenue for small and efficient fluorescent markers in imaging and sensing applications. |
| first_indexed | 2024-03-11T02:12:37Z |
| format | Article |
| id | doaj.art-9a725801312849daaa6c39f45c823c3f |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-11T02:12:37Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-9a725801312849daaa6c39f45c823c3f2023-11-18T11:25:04ZengMDPI AGMaterials1996-19442023-06-011612435410.3390/ma16124354Efficient Lithium-Based Upconversion Nanoparticles for Single-Particle Imaging and Temperature SensingYahya A. Alzahrani0Abdulaziz Alromaeh1Masfer Alkahtani2Future Energy Technologies Institute, King Abdulaziz City for Science and Technology (KACST), Riyadh 11442, Saudi ArabiaMicroelectronics and Semiconductors Institute, King Abdulaziz City for Science and Technology (KACST), Riyadh 11442, Saudi ArabiaFuture Energy Technologies Institute, King Abdulaziz City for Science and Technology (KACST), Riyadh 11442, Saudi ArabiaUpconversion Nanoparticles (UCNPs) have attracted exceptional attention due to their great potential in high-contrast, free-background biofluorescence deep tissue imaging and quantum sensing. Most of these interesting studies have been performed using an ensemble of UCNPs as fluorescent probes in bioapplications. Here, we report a synthesis of small and efficient YLiF<sub>4</sub>:Yb,Er UCNPs for single-particle imaging as well as sensitive optical temperature sensing. The reported particles demonstrated a bright and photostable upconversion emission at a single particle level under a low laser intensity excitation of 20 W/cm<sup>2</sup>. Furthermore, the synthesized UCNPs were tested and compared to the commonly used two-photon excitation QDs and organic dyes and showed a nine times better performance at a single particle level under the same experimental conditions. In addition, the synthesized UCNPs demonstrated sensitive optical temperature sensing at a single particle level within the biological temperature range. The good optical properties of single YLiF<sub>4</sub>:Yb,Er UCNPs open an avenue for small and efficient fluorescent markers in imaging and sensing applications.https://www.mdpi.com/1996-1944/16/12/4354upconversion nanoparticlestemperaturesingle-particle imagingquantum sensing |
| spellingShingle | Yahya A. Alzahrani Abdulaziz Alromaeh Masfer Alkahtani Efficient Lithium-Based Upconversion Nanoparticles for Single-Particle Imaging and Temperature Sensing Materials upconversion nanoparticles temperature single-particle imaging quantum sensing |
| title | Efficient Lithium-Based Upconversion Nanoparticles for Single-Particle Imaging and Temperature Sensing |
| title_full | Efficient Lithium-Based Upconversion Nanoparticles for Single-Particle Imaging and Temperature Sensing |
| title_fullStr | Efficient Lithium-Based Upconversion Nanoparticles for Single-Particle Imaging and Temperature Sensing |
| title_full_unstemmed | Efficient Lithium-Based Upconversion Nanoparticles for Single-Particle Imaging and Temperature Sensing |
| title_short | Efficient Lithium-Based Upconversion Nanoparticles for Single-Particle Imaging and Temperature Sensing |
| title_sort | efficient lithium based upconversion nanoparticles for single particle imaging and temperature sensing |
| topic | upconversion nanoparticles temperature single-particle imaging quantum sensing |
| url | https://www.mdpi.com/1996-1944/16/12/4354 |
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