Characterization of a Sulfhydryl Oxidase From Plasmodium berghei as a Target for Blocking Parasite Transmission

Characterization of a Sulfhydryl Oxidase From Plasmodium berghei as a Target for Blocking Parasite Transmission

Quiescin sulfhydryl oxidase (QSOX), present in a wide variety of eukaryotic species, catalyzes the insertion of disulfide bonds into unfolded, reduced proteins. Here we characterized the QSOX protein from the rodent malaria parasite Plasmodium berghei (PbQSOX), which is conserved in all sequenced ma...

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Bibliographic Details
Main Authors: Wenqi Zheng, Fei Liu, Feng Du, Fan Yang, Xu Kou, Yiwen He, Hui Feng, Qi Fan, Enjie Luo, Hui Min, Jun Miao, Liwang Cui, Yaming Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
malaria
Plasmodium berghei
quiescin sulfhydryl oxidase
sexual development
transmission-blocking vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00311/full

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