Cannabinoid Receptor 1/miR-30b-5p Axis Governs Macrophage NLRP3 Expression and Inflammasome Activation in Liver Inflammatory Disease

Cannabinoid Receptor 1/miR-30b-5p Axis Governs Macrophage NLRP3 Expression and Inflammasome Activation in Liver Inflammatory Disease

Nod-like receptor (NLR) family pyrin domain containing 3 (NLRP3) has been regarded as an important initiator or promoter in multiple inflammatory diseases. However, the relationship between cannabinoid receptor 1 (CB1) and macrophage NLRP3 inflammasome and the corresponding molecular mechanism in li...

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Bibliographic Details
Main Authors: Le Yang, Lei Tian, Zhi Zhang, Xuan Zhou, Xiaofang Ji, Fuquan Liu, Chengbin Dong, Lei Hou, Xinhao Zhao, Na Chang, Lin Yang, Liying Li
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
microRNA-30b-5p
cannabinoid receptor 1
macrophage
NLRP3
liver inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301189

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