Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature
<p>Abstract</p> <p>Libman-Sacks endocarditis of the mitral valve was first described by Libman and Sacks in 1924. Currently, the sterile verrucous vegetative lesions seen in Libman-Sacks endocarditis are regarded as a cardiac manifestation of both systemic lupus erythematosus (SLE)...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-03-01
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| Series: | Journal of Cardiothoracic Surgery |
| Online Access: | http://www.cardiothoracicsurgery.org/content/5/1/13 |
| _version_ | 1811329402059882496 |
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| author | Bijl Marc Erasmus Michiel E Wijdh-den Hamer Inez J van der Horst Iwan CC Klinkenberg Theo J Bouma Wobbe Suurmeijer Albert JH Zijlstra Felix Mariani Massimo A |
| author_facet | Bijl Marc Erasmus Michiel E Wijdh-den Hamer Inez J van der Horst Iwan CC Klinkenberg Theo J Bouma Wobbe Suurmeijer Albert JH Zijlstra Felix Mariani Massimo A |
| author_sort | Bijl Marc |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Libman-Sacks endocarditis of the mitral valve was first described by Libman and Sacks in 1924. Currently, the sterile verrucous vegetative lesions seen in Libman-Sacks endocarditis are regarded as a cardiac manifestation of both systemic lupus erythematosus (SLE) and the antiphospholipid syndrome (APS). Although typically mild and asymptomatic, complications of Libman-Sacks endocarditis may include superimposed bacterial endocarditis, thromboembolic events, and severe valvular regurgitation and/or stenosis requiring surgery. In this study we report two cases of mitral valve repair and two cases of mitral valve replacement for mitral regurgitation (MR) caused by Libman-Sacks endocarditis. In addition, we provide a systematic review of the English literature on mitral valve surgery for MR caused by Libman-Sacks endocarditis. This report shows that mitral valve repair is feasible and effective in young patients with relatively stable SLE and/or APS and only localized mitral valve abnormalities caused by Libman-Sacks endocarditis. Both clinical and echocardiographic follow-up after repair show excellent mid- and long-term results.</p> |
| first_indexed | 2024-04-13T15:43:15Z |
| format | Article |
| id | doaj.art-9a7a4ccd4ac74a62b3ba87111c1be8b7 |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-04-13T15:43:15Z |
| publishDate | 2010-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-9a7a4ccd4ac74a62b3ba87111c1be8b72022-12-22T02:41:04ZengBMCJournal of Cardiothoracic Surgery1749-80902010-03-01511310.1186/1749-8090-5-13Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literatureBijl MarcErasmus Michiel EWijdh-den Hamer Inez Jvan der Horst Iwan CCKlinkenberg Theo JBouma WobbeSuurmeijer Albert JHZijlstra FelixMariani Massimo A<p>Abstract</p> <p>Libman-Sacks endocarditis of the mitral valve was first described by Libman and Sacks in 1924. Currently, the sterile verrucous vegetative lesions seen in Libman-Sacks endocarditis are regarded as a cardiac manifestation of both systemic lupus erythematosus (SLE) and the antiphospholipid syndrome (APS). Although typically mild and asymptomatic, complications of Libman-Sacks endocarditis may include superimposed bacterial endocarditis, thromboembolic events, and severe valvular regurgitation and/or stenosis requiring surgery. In this study we report two cases of mitral valve repair and two cases of mitral valve replacement for mitral regurgitation (MR) caused by Libman-Sacks endocarditis. In addition, we provide a systematic review of the English literature on mitral valve surgery for MR caused by Libman-Sacks endocarditis. This report shows that mitral valve repair is feasible and effective in young patients with relatively stable SLE and/or APS and only localized mitral valve abnormalities caused by Libman-Sacks endocarditis. Both clinical and echocardiographic follow-up after repair show excellent mid- and long-term results.</p>http://www.cardiothoracicsurgery.org/content/5/1/13 |
| spellingShingle | Bijl Marc Erasmus Michiel E Wijdh-den Hamer Inez J van der Horst Iwan CC Klinkenberg Theo J Bouma Wobbe Suurmeijer Albert JH Zijlstra Felix Mariani Massimo A Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature Journal of Cardiothoracic Surgery |
| title | Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature |
| title_full | Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature |
| title_fullStr | Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature |
| title_full_unstemmed | Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature |
| title_short | Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature |
| title_sort | mitral valve surgery for mitral regurgitation caused by libman sacks endocarditis a report of four cases and a systematic review of the literature |
| url | http://www.cardiothoracicsurgery.org/content/5/1/13 |
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