Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas
This work demonstrates the safety and feasibility of Lattice Radiotherapy (LRT) for large soft tissue sarcoma in neoadjuvant radiotherapy. The treatment consisted of two courses: the LRT course with a single fraction of 20 Gy delivered to high dose nuclei (HDN) regions and the conventional course wi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-04-01
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| Series: | Physics and Imaging in Radiation Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405631622000392 |
| _version_ | 1818545538309554176 |
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| author | Egor Borzov Raquel Bar-Deroma Myroslav Lutsyk |
| author_facet | Egor Borzov Raquel Bar-Deroma Myroslav Lutsyk |
| author_sort | Egor Borzov |
| collection | DOAJ |
| description | This work demonstrates the safety and feasibility of Lattice Radiotherapy (LRT) for large soft tissue sarcoma in neoadjuvant radiotherapy. The treatment consisted of two courses: the LRT course with a single fraction of 20 Gy delivered to high dose nuclei (HDN) regions and the conventional course with 25 fractions of 2 Gy delivered to the planning target volume. HDN shaped as cylinders with a 1 cm diameter and 1 cm height were placed within the gross tumour volume. The number of HDNs and their position were determined based on tumor size and proximity to organs at risk. Three patients were irradiated using the LRT technique. |
| first_indexed | 2024-12-12T07:41:27Z |
| format | Article |
| id | doaj.art-9a7ba753a2f64eda90d8ebb3e1891857 |
| institution | Directory Open Access Journal |
| issn | 2405-6316 |
| language | English |
| last_indexed | 2024-12-12T07:41:27Z |
| publishDate | 2022-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Physics and Imaging in Radiation Oncology |
| spelling | doaj.art-9a7ba753a2f64eda90d8ebb3e18918572022-12-22T00:32:47ZengElsevierPhysics and Imaging in Radiation Oncology2405-63162022-04-01226366Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomasEgor Borzov0Raquel Bar-Deroma1Myroslav Lutsyk2Corresponding author at: HaAliya HaShniya St 8, Haifa 3109601, Israel.; Department of Radiotherapy, Division of Oncology, Rambam Health Care Campus, Haifa 32000, IsraelDepartment of Radiotherapy, Division of Oncology, Rambam Health Care Campus, Haifa 32000, IsraelDepartment of Radiotherapy, Division of Oncology, Rambam Health Care Campus, Haifa 32000, IsraelThis work demonstrates the safety and feasibility of Lattice Radiotherapy (LRT) for large soft tissue sarcoma in neoadjuvant radiotherapy. The treatment consisted of two courses: the LRT course with a single fraction of 20 Gy delivered to high dose nuclei (HDN) regions and the conventional course with 25 fractions of 2 Gy delivered to the planning target volume. HDN shaped as cylinders with a 1 cm diameter and 1 cm height were placed within the gross tumour volume. The number of HDNs and their position were determined based on tumor size and proximity to organs at risk. Three patients were irradiated using the LRT technique.http://www.sciencedirect.com/science/article/pii/S2405631622000392GRIDLRTSFRTSoft tissue sarcoma |
| spellingShingle | Egor Borzov Raquel Bar-Deroma Myroslav Lutsyk Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas Physics and Imaging in Radiation Oncology GRID LRT SFRT Soft tissue sarcoma |
| title | Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas |
| title_full | Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas |
| title_fullStr | Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas |
| title_full_unstemmed | Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas |
| title_short | Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas |
| title_sort | physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas |
| topic | GRID LRT SFRT Soft tissue sarcoma |
| url | http://www.sciencedirect.com/science/article/pii/S2405631622000392 |
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