Identification of factors associated with duplicate rate in ChIP-seq data.

Chromatin immunoprecipitation and sequencing (ChIP-seq) has been widely used to map DNA-binding proteins, histone proteins and their modifications. ChIP-seq data contains redundant reads termed duplicates, referring to those mapping to the same genomic location and strand. There are two main sources...

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Bibliographic Details
Main Authors: Shulan Tian, Shuxia Peng, Michael Kalmbach, Krutika S Gaonkar, Aditya Bhagwate, Wei Ding, Jeanette Eckel-Passow, Huihuang Yan, Susan L Slager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214723