KCa3.1 Channels Promote Cardiac Fibrosis Through Mediating Inflammation and Differentiation of Monocytes Into Myofibroblasts in Angiotensin II–Treated Rats

Background Cardiac fibrosis is a core pathological process associated with heart failure. The recruitment and differentiation of primitive fibroblast precursor cells of bone marrow origin play a critical role in pathological interstitial cardiac fibrosis. The KCa3.1 channels are expressed in both ve...

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Bibliographic Details
Main Authors: Gang She, Yu‐Jie Ren, Yan Wang, Meng‐Chen Hou, Hui‐Fang Wang, Wei Gou, Bao‐Chang Lai, Ting Lei, Xiao‐Jun Du, Xiu‐Ling Deng
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.010418