Knockdown of TACC3 inhibits tumor cell proliferation and increases chemosensitivity in pancreatic cancer

Knockdown of TACC3 inhibits tumor cell proliferation and increases chemosensitivity in pancreatic cancer

Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant digestive tract tumor with limited clinical treatments. Transforming acidic coiled-coil-containing protein 3 (TACC3) is a component of the centrosome axis and a member of the TACC family, which affect mitosis and regulate chromos...

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Bibliographic Details
Main Authors:	Saimeng Shi, Duancheng Guo, Longyun Ye, Tianjiao Li, Qinglin Fei, Mengxiong Lin, Xianjun Yu, Kaizhou Jin, Weiding Wu
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-11-01
Series:	Cell Death and Disease
Online Access:	https://doi.org/10.1038/s41419-023-06313-x

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