Voting Ensemble Approach for Enhancing Alzheimer’s Disease Classification

Alzheimer’s disease is dementia that impairs one’s thinking, behavior, and memory. It starts as a moderate condition affecting areas of the brain that make it challenging to retain recently learned information, causes mood swings, and causes confusion regarding occasions, times, and locations. The m...

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Main Authors: Subhajit Chatterjee, Yung-Cheol Byun
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/19/7661
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author Subhajit Chatterjee
Yung-Cheol Byun
author_facet Subhajit Chatterjee
Yung-Cheol Byun
author_sort Subhajit Chatterjee
collection DOAJ
description Alzheimer’s disease is dementia that impairs one’s thinking, behavior, and memory. It starts as a moderate condition affecting areas of the brain that make it challenging to retain recently learned information, causes mood swings, and causes confusion regarding occasions, times, and locations. The most prevalent type of dementia, called Alzheimer’s disease (AD), causes memory-related problems in patients. A precise medical diagnosis that correctly classifies AD patients results in better treatment. Currently, the most commonly used classification techniques extract features from longitudinal MRI data before creating a single classifier that performs classification. However, it is difficult to train a reliable classifier to achieve acceptable classification performance due to limited sample size and noise in longitudinal MRI data. Instead of creating a single classifier, we propose an ensemble voting method that generates multiple individual classifier predictions and then combines them to develop a more accurate and reliable classifier. The ensemble voting classifier model performs better in the Open Access Series of Imaging Studies (OASIS) dataset for older adults than existing methods in important assessment criteria such as accuracy, sensitivity, specificity, and AUC. For the binary classification of with dementia and no dementia, an accuracy of 96.4% and an AUC of 97.2% is attained.
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spelling doaj.art-9a8a372fc637428eb0dc35c00b2e8a332023-11-23T21:52:44ZengMDPI AGSensors1424-82202022-10-012219766110.3390/s22197661Voting Ensemble Approach for Enhancing Alzheimer’s Disease ClassificationSubhajit Chatterjee0Yung-Cheol Byun1Department of Computer Engineering, Jeju National University, Jeju 63243, KoreaDepartment of Computer Engineering, Major of Electronic Engineering, Institute of Information Science & Technology, Jeju National University, Jeju 63243, KoreaAlzheimer’s disease is dementia that impairs one’s thinking, behavior, and memory. It starts as a moderate condition affecting areas of the brain that make it challenging to retain recently learned information, causes mood swings, and causes confusion regarding occasions, times, and locations. The most prevalent type of dementia, called Alzheimer’s disease (AD), causes memory-related problems in patients. A precise medical diagnosis that correctly classifies AD patients results in better treatment. Currently, the most commonly used classification techniques extract features from longitudinal MRI data before creating a single classifier that performs classification. However, it is difficult to train a reliable classifier to achieve acceptable classification performance due to limited sample size and noise in longitudinal MRI data. Instead of creating a single classifier, we propose an ensemble voting method that generates multiple individual classifier predictions and then combines them to develop a more accurate and reliable classifier. The ensemble voting classifier model performs better in the Open Access Series of Imaging Studies (OASIS) dataset for older adults than existing methods in important assessment criteria such as accuracy, sensitivity, specificity, and AUC. For the binary classification of with dementia and no dementia, an accuracy of 96.4% and an AUC of 97.2% is attained.https://www.mdpi.com/1424-8220/22/19/7661Alzheimer’s diseasedeep learningclassificationensemble learningMRI data
spellingShingle Subhajit Chatterjee
Yung-Cheol Byun
Voting Ensemble Approach for Enhancing Alzheimer’s Disease Classification
Sensors
Alzheimer’s disease
deep learning
classification
ensemble learning
MRI data
title Voting Ensemble Approach for Enhancing Alzheimer’s Disease Classification
title_full Voting Ensemble Approach for Enhancing Alzheimer’s Disease Classification
title_fullStr Voting Ensemble Approach for Enhancing Alzheimer’s Disease Classification
title_full_unstemmed Voting Ensemble Approach for Enhancing Alzheimer’s Disease Classification
title_short Voting Ensemble Approach for Enhancing Alzheimer’s Disease Classification
title_sort voting ensemble approach for enhancing alzheimer s disease classification
topic Alzheimer’s disease
deep learning
classification
ensemble learning
MRI data
url https://www.mdpi.com/1424-8220/22/19/7661
work_keys_str_mv AT subhajitchatterjee votingensembleapproachforenhancingalzheimersdiseaseclassification
AT yungcheolbyun votingensembleapproachforenhancingalzheimersdiseaseclassification