Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida Biofilm
Ten banana (<i>Musa</i> spp.) cultivars were studied for their antimicrobial properties. Three plant parts (corm, pseudostem and leaves) were collected separately and extracted with different solvents, viz., hexane, acetone, ethanol and water. The 50% inhibitory concentration (IC<sub&...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/9/4/435 |
| _version_ | 1827719290320584704 |
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| author | Ramin Saleh Jouneghani Ana Hortência Fonsêca Castro Sujogya Kumar Panda Rony Swennen Walter Luyten |
| author_facet | Ramin Saleh Jouneghani Ana Hortência Fonsêca Castro Sujogya Kumar Panda Rony Swennen Walter Luyten |
| author_sort | Ramin Saleh Jouneghani |
| collection | DOAJ |
| description | Ten banana (<i>Musa</i> spp.) cultivars were studied for their antimicrobial properties. Three plant parts (corm, pseudostem and leaves) were collected separately and extracted with different solvents, viz., hexane, acetone, ethanol and water. The 50% inhibitory concentration (IC<sub>50</sub>) was evaluated using a broth microdilution assay. Eight human bacterial and one fungal pathogen were tested. Acetone and ethanol extract(s) often exhibited significant antimicrobial activity, while hexane extracts were less active. Aqueous extracts often showed microbial growth, possibly by endophytes. Leaf extracts were most active, followed by pseudostem, and corm was least active. All the tested banana cultivars were found to contain antimicrobials, as demonstrated by inhibition of selected human pathogens. However, cultivars such as Dole, Saba, Fougamou, Namwah Khom, Pelipita and Mbwazirume showed a broad-spectrum activity, inhibiting all tested pathogens. Other cultivars such as Petit Naine and Kluai Tiparot showed a narrow-spectrum activity, including antibiofilm activity against <i>Candida albicans</i>. Our results support the use of different parts of banana plants in traditional human medicine for infections, including diarrhea and dysentery, and some sexually transmitted diseases, as well as for packaging spoilable materials like food. |
| first_indexed | 2024-03-10T20:40:15Z |
| format | Article |
| id | doaj.art-9a8c4957331b4823be7b3b69b8d084a2 |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-10T20:40:15Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-9a8c4957331b4823be7b3b69b8d084a22023-11-19T20:43:20ZengMDPI AGFoods2304-81582020-04-019443510.3390/foods9040435Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida BiofilmRamin Saleh Jouneghani0Ana Hortência Fonsêca Castro1Sujogya Kumar Panda2Rony Swennen3Walter Luyten4Department of Biology, Katholieke Universiteit Leuven, 3000 Leuven, BelgiumDepartment of Biology, Katholieke Universiteit Leuven, 3000 Leuven, BelgiumDepartment of Biology, Katholieke Universiteit Leuven, 3000 Leuven, BelgiumInternational Institute of Tropical Agriculture, Arusha 447, TanzaniaDepartment of Biology, Katholieke Universiteit Leuven, 3000 Leuven, BelgiumTen banana (<i>Musa</i> spp.) cultivars were studied for their antimicrobial properties. Three plant parts (corm, pseudostem and leaves) were collected separately and extracted with different solvents, viz., hexane, acetone, ethanol and water. The 50% inhibitory concentration (IC<sub>50</sub>) was evaluated using a broth microdilution assay. Eight human bacterial and one fungal pathogen were tested. Acetone and ethanol extract(s) often exhibited significant antimicrobial activity, while hexane extracts were less active. Aqueous extracts often showed microbial growth, possibly by endophytes. Leaf extracts were most active, followed by pseudostem, and corm was least active. All the tested banana cultivars were found to contain antimicrobials, as demonstrated by inhibition of selected human pathogens. However, cultivars such as Dole, Saba, Fougamou, Namwah Khom, Pelipita and Mbwazirume showed a broad-spectrum activity, inhibiting all tested pathogens. Other cultivars such as Petit Naine and Kluai Tiparot showed a narrow-spectrum activity, including antibiofilm activity against <i>Candida albicans</i>. Our results support the use of different parts of banana plants in traditional human medicine for infections, including diarrhea and dysentery, and some sexually transmitted diseases, as well as for packaging spoilable materials like food.https://www.mdpi.com/2304-8158/9/4/435antimicrobial activitybanana cultivarsbiofilm inhibitory concentrationfood-borne pathogens<i>Musa</i> spp. |
| spellingShingle | Ramin Saleh Jouneghani Ana Hortência Fonsêca Castro Sujogya Kumar Panda Rony Swennen Walter Luyten Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida Biofilm Foods antimicrobial activity banana cultivars biofilm inhibitory concentration food-borne pathogens <i>Musa</i> spp. |
| title | Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida Biofilm |
| title_full | Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida Biofilm |
| title_fullStr | Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida Biofilm |
| title_full_unstemmed | Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida Biofilm |
| title_short | Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida Biofilm |
| title_sort | antimicrobial activity of selected banana cultivars against important human pathogens including candida biofilm |
| topic | antimicrobial activity banana cultivars biofilm inhibitory concentration food-borne pathogens <i>Musa</i> spp. |
| url | https://www.mdpi.com/2304-8158/9/4/435 |
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