Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis
<p>Abstract</p> <p>Background</p> <p>Pancreatic ductal adenocarcinoma shows a distinct apoptosis resistance, which contributes significantly to the aggressive nature of this tumor and constrains the effectiveness of new therapeutic strategies. Apoptosis resistance is de...
Main Authors: | Grützmann Robert, Saeger Hans-Detlev, Lehner Anne-Kathrin, Samm Nicole, Rückert Felix, Pilarsky Christian |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-07-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/10/379 |
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