Confirmation of quantitative trait loci affecting fatness in chickens

<p>Abstract</p> <p>In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created...

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Bibliographic Details
Main Authors: Poel Jan, Crooijmans Richard MPA, Vereijken Addie LJ, Bovenhuis Henk, Jennen Danyel GJ, Groenen Martien AM
Format: Article
Language:deu
Published: BMC 2005-03-01
Series:Genetics Selection Evolution
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Online Access:http://www.gsejournal.org/content/37/3/215
Description
Summary:<p>Abstract</p> <p>In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G<sub>2</sub>) onwards until generation 9 (G<sub>9</sub>) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G<sub>9 </sub>population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold.</p>
ISSN:0999-193X
1297-9686