Using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trial
Abstract Background Total knee arthroplasty (TKA) is a gold standard for patients with terminal term gonarthrosis for reducing pain, correcting deformities, and regaining stability. However, post-TKA muscle strength recovery is often difficult. Although electroacupuncture (EA) enhances lower extremi...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-08-01
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| Series: | Trials |
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| Online Access: | http://link.springer.com/article/10.1186/s13063-020-04601-x |
| _version_ | 1811322740921073664 |
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| author | Hui Xu Bingxin Kang Yulin Li Jun Xie Songtao Sun Sheng Zhong Chenxin Gao Xirui Xu Chi Zhao Guowei Qiu Lianbo Xiao |
| author_facet | Hui Xu Bingxin Kang Yulin Li Jun Xie Songtao Sun Sheng Zhong Chenxin Gao Xirui Xu Chi Zhao Guowei Qiu Lianbo Xiao |
| author_sort | Hui Xu |
| collection | DOAJ |
| description | Abstract Background Total knee arthroplasty (TKA) is a gold standard for patients with terminal term gonarthrosis for reducing pain, correcting deformities, and regaining stability. However, post-TKA muscle strength recovery is often difficult. Although electroacupuncture (EA) enhances lower extremity muscle strength of the lower extremity, there is limited evidence regarding its effect on lower extremity muscle strength in post-TKA patients. Consequently, this trial intends to evaluate the efficacy of post-TKA EA on the recovery of lower extremity muscle strength, specifically, during the early post-TKA period. Methods/design This is a double-blinded, randomized, and controlled trial. It will be conducted between August 2020 and December 2020. Ninety-four participants with KOA who have undergone unilateral TKA will be randomized into a treatment (EA) group and a control (sham EA) group. The former and latter groups will receive EA and sham EA, respectively, at ST37, ST36, SP10, and SP9 acupoints. The participants will undergo ten treatment sessions over 2 weeks (5 sessions per week). The primary outcomes will include changes in muscle strength and the Hospital for Special Surgery score at the second week from baseline (pre-op 1 day or POD 3). The secondary outcomes will include a 4-m walk test, numerical rating scale score, the Hamilton Anxiety Scale score, and additional analgesia use. Additional outcomes will include the incidence of analgesia-related side effects and the participant satisfaction rate. Participant blinding will also be assessed where they will be asked to guess whether they received EA after the latest intervention. Adverse EA events will be documented and assessed throughout the trial. Discussion EA is helpful for post-TKA recovery and enhancement of lower limb muscle strength. Trial registration Chinese Clinical Trial Registry ChiCTR1900027806 . Registered on 29 November 2019 |
| first_indexed | 2024-04-13T13:40:17Z |
| format | Article |
| id | doaj.art-9a907ade5c9742cda305a09b6627e0c6 |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-04-13T13:40:17Z |
| publishDate | 2020-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Trials |
| spelling | doaj.art-9a907ade5c9742cda305a09b6627e0c62022-12-22T02:44:39ZengBMCTrials1745-62152020-08-012111910.1186/s13063-020-04601-xUsing electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trialHui Xu0Bingxin Kang1Yulin Li2Jun Xie3Songtao Sun4Sheng Zhong5Chenxin Gao6Xirui Xu7Chi Zhao8Guowei Qiu9Lianbo Xiao10Department of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineShanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese MedicineAbstract Background Total knee arthroplasty (TKA) is a gold standard for patients with terminal term gonarthrosis for reducing pain, correcting deformities, and regaining stability. However, post-TKA muscle strength recovery is often difficult. Although electroacupuncture (EA) enhances lower extremity muscle strength of the lower extremity, there is limited evidence regarding its effect on lower extremity muscle strength in post-TKA patients. Consequently, this trial intends to evaluate the efficacy of post-TKA EA on the recovery of lower extremity muscle strength, specifically, during the early post-TKA period. Methods/design This is a double-blinded, randomized, and controlled trial. It will be conducted between August 2020 and December 2020. Ninety-four participants with KOA who have undergone unilateral TKA will be randomized into a treatment (EA) group and a control (sham EA) group. The former and latter groups will receive EA and sham EA, respectively, at ST37, ST36, SP10, and SP9 acupoints. The participants will undergo ten treatment sessions over 2 weeks (5 sessions per week). The primary outcomes will include changes in muscle strength and the Hospital for Special Surgery score at the second week from baseline (pre-op 1 day or POD 3). The secondary outcomes will include a 4-m walk test, numerical rating scale score, the Hamilton Anxiety Scale score, and additional analgesia use. Additional outcomes will include the incidence of analgesia-related side effects and the participant satisfaction rate. Participant blinding will also be assessed where they will be asked to guess whether they received EA after the latest intervention. Adverse EA events will be documented and assessed throughout the trial. Discussion EA is helpful for post-TKA recovery and enhancement of lower limb muscle strength. Trial registration Chinese Clinical Trial Registry ChiCTR1900027806 . Registered on 29 November 2019http://link.springer.com/article/10.1186/s13063-020-04601-xElectroacupunctureKnee osteoarthritisTotal knee arthroplastyStudy protocol |
| spellingShingle | Hui Xu Bingxin Kang Yulin Li Jun Xie Songtao Sun Sheng Zhong Chenxin Gao Xirui Xu Chi Zhao Guowei Qiu Lianbo Xiao Using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trial Trials Electroacupuncture Knee osteoarthritis Total knee arthroplasty Study protocol |
| title | Using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trial |
| title_full | Using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trial |
| title_fullStr | Using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trial |
| title_full_unstemmed | Using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trial |
| title_short | Using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trial |
| title_sort | using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty a study protocol for a double blinded randomized and placebo controlled trial |
| topic | Electroacupuncture Knee osteoarthritis Total knee arthroplasty Study protocol |
| url | http://link.springer.com/article/10.1186/s13063-020-04601-x |
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