Graft healing after anterior cruciate ligament reconstruction (ACLR)

Anterior cruciate ligament reconstruction (ACLR) is a commonly performed procedure in Orthopaedic sports medicine. With advances in surgical techniques providing better positioning and fixation of the graft, subsequent graft failure to certain extent should be accounted by poor graft healing. Althou...

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Main Authors: Shiyi Yao, Bruma Sai-Chuen Fu, Patrick Shu-Hang Yung
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221468732100008X
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author Shiyi Yao
Bruma Sai-Chuen Fu
Patrick Shu-Hang Yung
author_facet Shiyi Yao
Bruma Sai-Chuen Fu
Patrick Shu-Hang Yung
author_sort Shiyi Yao
collection DOAJ
description Anterior cruciate ligament reconstruction (ACLR) is a commonly performed procedure in Orthopaedic sports medicine. With advances in surgical techniques providing better positioning and fixation of the graft, subsequent graft failure to certain extent should be accounted by poor graft healing. Although different biological modulations for enhancement of graft healing have been tried in different clinical and animal studies, complete graft incorporation into bone tunnels and the “ligamentization” of the intra-articular part have not been fully achieved yet. Based on the understanding of graft healing process and its failure mechanism, the purpose of this review is to combine both the known basic science & clinical evidence, to provide a much clearer picture of the obstacle encountered in graft healing, so as to facilitate researchers on subsequent work on the enhancement of ACL graft healing.
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spelling doaj.art-9a922f6f76da4510a23a820ceb2107b82022-12-21T22:35:30ZengElsevierAsia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology2214-68732021-07-0125815Graft healing after anterior cruciate ligament reconstruction (ACLR)Shiyi Yao0Bruma Sai-Chuen Fu1Patrick Shu-Hang Yung2Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong KongDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong KongCorresponding author.; Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong KongAnterior cruciate ligament reconstruction (ACLR) is a commonly performed procedure in Orthopaedic sports medicine. With advances in surgical techniques providing better positioning and fixation of the graft, subsequent graft failure to certain extent should be accounted by poor graft healing. Although different biological modulations for enhancement of graft healing have been tried in different clinical and animal studies, complete graft incorporation into bone tunnels and the “ligamentization” of the intra-articular part have not been fully achieved yet. Based on the understanding of graft healing process and its failure mechanism, the purpose of this review is to combine both the known basic science & clinical evidence, to provide a much clearer picture of the obstacle encountered in graft healing, so as to facilitate researchers on subsequent work on the enhancement of ACL graft healing.http://www.sciencedirect.com/science/article/pii/S221468732100008XAnterior cruciate ligament reconstruction (ACLR)Graft healing process. biological modulationGraft failure
spellingShingle Shiyi Yao
Bruma Sai-Chuen Fu
Patrick Shu-Hang Yung
Graft healing after anterior cruciate ligament reconstruction (ACLR)
Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology
Anterior cruciate ligament reconstruction (ACLR)
Graft healing process. biological modulation
Graft failure
title Graft healing after anterior cruciate ligament reconstruction (ACLR)
title_full Graft healing after anterior cruciate ligament reconstruction (ACLR)
title_fullStr Graft healing after anterior cruciate ligament reconstruction (ACLR)
title_full_unstemmed Graft healing after anterior cruciate ligament reconstruction (ACLR)
title_short Graft healing after anterior cruciate ligament reconstruction (ACLR)
title_sort graft healing after anterior cruciate ligament reconstruction aclr
topic Anterior cruciate ligament reconstruction (ACLR)
Graft healing process. biological modulation
Graft failure
url http://www.sciencedirect.com/science/article/pii/S221468732100008X
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AT brumasaichuenfu grafthealingafteranteriorcruciateligamentreconstructionaclr
AT patrickshuhangyung grafthealingafteranteriorcruciateligamentreconstructionaclr