Negri bodies are viral factories with properties of liquid organelles
Negative strand RNA viruses, such as rabies virus, induce formation of cytoplasmic inclusions for genome replication. Here, Nikolic et al. show that these so-called Negri bodies (NBs) have characteristics of liquid organelles and they identify the minimal protein domains required for NB formation.
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-00102-9 |
| _version_ | 1818851295264505856 |
|---|---|
| author | Jovan Nikolic Romain Le Bars Zoé Lama Nathalie Scrima Cécile Lagaudrière-Gesbert Yves Gaudin Danielle Blondel |
| author_facet | Jovan Nikolic Romain Le Bars Zoé Lama Nathalie Scrima Cécile Lagaudrière-Gesbert Yves Gaudin Danielle Blondel |
| author_sort | Jovan Nikolic |
| collection | DOAJ |
| description | Negative strand RNA viruses, such as rabies virus, induce formation of cytoplasmic inclusions for genome replication. Here, Nikolic et al. show that these so-called Negri bodies (NBs) have characteristics of liquid organelles and they identify the minimal protein domains required for NB formation. |
| first_indexed | 2024-12-19T07:02:45Z |
| format | Article |
| id | doaj.art-9a955e81f9324d589e3ef61679b3fd39 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T07:02:45Z |
| publishDate | 2017-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9a955e81f9324d589e3ef61679b3fd392022-12-21T20:31:22ZengNature PortfolioNature Communications2041-17232017-07-018111310.1038/s41467-017-00102-9Negri bodies are viral factories with properties of liquid organellesJovan Nikolic0Romain Le Bars1Zoé Lama2Nathalie Scrima3Cécile Lagaudrière-Gesbert4Yves Gaudin5Danielle Blondel6Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-SaclayInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-SaclayInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-SaclayInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-SaclayInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-SaclayInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-SaclayInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-SaclayNegative strand RNA viruses, such as rabies virus, induce formation of cytoplasmic inclusions for genome replication. Here, Nikolic et al. show that these so-called Negri bodies (NBs) have characteristics of liquid organelles and they identify the minimal protein domains required for NB formation.https://doi.org/10.1038/s41467-017-00102-9 |
| spellingShingle | Jovan Nikolic Romain Le Bars Zoé Lama Nathalie Scrima Cécile Lagaudrière-Gesbert Yves Gaudin Danielle Blondel Negri bodies are viral factories with properties of liquid organelles Nature Communications |
| title | Negri bodies are viral factories with properties of liquid organelles |
| title_full | Negri bodies are viral factories with properties of liquid organelles |
| title_fullStr | Negri bodies are viral factories with properties of liquid organelles |
| title_full_unstemmed | Negri bodies are viral factories with properties of liquid organelles |
| title_short | Negri bodies are viral factories with properties of liquid organelles |
| title_sort | negri bodies are viral factories with properties of liquid organelles |
| url | https://doi.org/10.1038/s41467-017-00102-9 |
| work_keys_str_mv | AT jovannikolic negribodiesareviralfactorieswithpropertiesofliquidorganelles AT romainlebars negribodiesareviralfactorieswithpropertiesofliquidorganelles AT zoelama negribodiesareviralfactorieswithpropertiesofliquidorganelles AT nathaliescrima negribodiesareviralfactorieswithpropertiesofliquidorganelles AT cecilelagaudrieregesbert negribodiesareviralfactorieswithpropertiesofliquidorganelles AT yvesgaudin negribodiesareviralfactorieswithpropertiesofliquidorganelles AT danielleblondel negribodiesareviralfactorieswithpropertiesofliquidorganelles |