The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patients
Background and aim: Non-alcoholic steatohepatitis is a part of broad spectrum of chronic non-alcoholic fatty liver disease. The aim of present study was to evaluate the effect of 12 weeks vitamin E supplementation and aerobic training on liver enzymes level of non-alcoholic steatohepatitis...
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| Format: | Article |
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Yasuj University Of Medical Sciences
2017-01-01
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| Series: | Armaghane Danesh Bimonthly Journal |
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| Online Access: | http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-793-1&slc_lang=en&sid=1 |
| _version_ | 1811199269055496192 |
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| author | M Aghah F Daryanoosh M Moeini M Mohamadi MR Fatahi |
| author_facet | M Aghah F Daryanoosh M Moeini M Mohamadi MR Fatahi |
| author_sort | M Aghah |
| collection | DOAJ |
| description | Background and aim: Non-alcoholic steatohepatitis is a part of broad spectrum of chronic non-alcoholic fatty liver disease. The aim of present study was to evaluate the effect of 12 weeks vitamin E supplementation and aerobic training on liver enzymes level of non-alcoholic steatohepatitis patients (NASH).
Methods: In the present quasi-experimental study, 30 NASH patients, aged 25-50 years were participated, and divided into three groups of vitamin E (n=10), aerobic training (n=10) and combination (aerobic training plus vitamin E, n=10) randomly. Vitamin E Supplementation and aerobic training combination groups consumed 400 IU per day of Vitamin E Supplementation. Also in the group of aerobic exercise and combined, exercise program including the increasing activity of anaerobic (running on a treadmill with increasing intensity every two weeks 5%) was carried out three times a week for 12 weeks. Data evaluation were analyzed using t-test, ANOVA and Scheffe.
Results: A significant differences was observed ALT (intra-group) of vitamin E (0001/0 = p) aerobic exercise (0001/0 = p) and combination (001/0 = p), respectively.There was a significant difference was seen among pre – post training in AST in supplementation(P=0.001), aerobic training(P=0.001) and combination (P=0.002) groups. But no significant difference in ALP level observed(P>0.05). In comparison among the groups, a significant differences was observed between groups ALP vitamin E, combination aerobic exercise but no significant difference was observed among the groups at the levels of ALT and AST.
Conclusion: The results of this study showed that vitamin E supplementation and aerobic training can improve non-alcoholic steatohepatitis Patients (NASH).
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| first_indexed | 2024-04-12T01:45:02Z |
| format | Article |
| id | doaj.art-9a967e02794c4a95a52dd8aa0ac1f3c2 |
| institution | Directory Open Access Journal |
| issn | 1728-6514 1728-6506 |
| language | fas |
| last_indexed | 2024-04-12T01:45:02Z |
| publishDate | 2017-01-01 |
| publisher | Yasuj University Of Medical Sciences |
| record_format | Article |
| series | Armaghane Danesh Bimonthly Journal |
| spelling | doaj.art-9a967e02794c4a95a52dd8aa0ac1f3c22022-12-22T03:53:06ZfasYasuj University Of Medical SciencesArmaghane Danesh Bimonthly Journal1728-65141728-65062017-01-012110964975The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patientsM Aghah0F Daryanoosh1M Moeini2M Mohamadi3MR Fatahi4 Department of Exercise Physiology, University of Shiraz, Shiraz,Iran Department of Exercise Physiology, University of Shiraz, Shiraz,Iran Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Educational Administration and Planning, School of Education and Psychology, University of Shiraz, Shiraz, Iran Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Background and aim: Non-alcoholic steatohepatitis is a part of broad spectrum of chronic non-alcoholic fatty liver disease. The aim of present study was to evaluate the effect of 12 weeks vitamin E supplementation and aerobic training on liver enzymes level of non-alcoholic steatohepatitis patients (NASH). Methods: In the present quasi-experimental study, 30 NASH patients, aged 25-50 years were participated, and divided into three groups of vitamin E (n=10), aerobic training (n=10) and combination (aerobic training plus vitamin E, n=10) randomly. Vitamin E Supplementation and aerobic training combination groups consumed 400 IU per day of Vitamin E Supplementation. Also in the group of aerobic exercise and combined, exercise program including the increasing activity of anaerobic (running on a treadmill with increasing intensity every two weeks 5%) was carried out three times a week for 12 weeks. Data evaluation were analyzed using t-test, ANOVA and Scheffe. Results: A significant differences was observed ALT (intra-group) of vitamin E (0001/0 = p) aerobic exercise (0001/0 = p) and combination (001/0 = p), respectively.There was a significant difference was seen among pre – post training in AST in supplementation(P=0.001), aerobic training(P=0.001) and combination (P=0.002) groups. But no significant difference in ALP level observed(P>0.05). In comparison among the groups, a significant differences was observed between groups ALP vitamin E, combination aerobic exercise but no significant difference was observed among the groups at the levels of ALT and AST. Conclusion: The results of this study showed that vitamin E supplementation and aerobic training can improve non-alcoholic steatohepatitis Patients (NASH). http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-793-1&slc_lang=en&sid=1Vitamin E Supplementation Aerobic training Non-alcoholic steatohepatitis |
| spellingShingle | M Aghah F Daryanoosh M Moeini M Mohamadi MR Fatahi The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patients Armaghane Danesh Bimonthly Journal Vitamin E Supplementation Aerobic training Non-alcoholic steatohepatitis |
| title | The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patients |
| title_full | The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patients |
| title_fullStr | The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patients |
| title_full_unstemmed | The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patients |
| title_short | The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patients |
| title_sort | effect of 12 weeks vitamin e supplemention and aerobic training on liver enzymes of non alcoholic steatohepatitis patients |
| topic | Vitamin E Supplementation Aerobic training Non-alcoholic steatohepatitis |
| url | http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-793-1&slc_lang=en&sid=1 |
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