C-reactive protein- and clinical symptoms-guided strategy in term neonates with early-onset sepsis reduced antibiotic use and hospital stay: a quality improvement initiative

C-reactive protein- and clinical symptoms-guided strategy in term neonates with early-onset sepsis reduced antibiotic use and hospital stay: a quality improvement initiative

Abstract Background Early-onset sepsis (EOS) is a potentially life-threatening complication of birth. Clinical symptoms are often unspecific and biomarkers have low predictive values for EOS. Therefore, clinical suspicion often leads to antibiotic therapy in neonates with a negative blood culture. I...

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Bibliographic Details
Main Authors: Johan Gyllensvärd, Fredrik Ingemansson, Elisabet Hentz, Marie Studahl, Anders Elfvin
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Pediatrics
Subjects:
Bacterial infection
C-reactive protein
Neonatal sepsis
Antibiotic therapy
Antibiotic stewardship
Quality improvement
Online Access:http://link.springer.com/article/10.1186/s12887-020-02426-w

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