Parity and Short-Term Estradiol Treatment Utilizes Similar Cellular Mechanisms to Confer Protection Against Breast Cancer

Parity and Short-Term Estradiol Treatment Utilizes Similar Cellular Mechanisms to Confer Protection Against Breast Cancer

Background: Protective effect of early pregnancy and short-term estrogen treatment (STET), against breast cancer is well established. The underlying mechanisms are not well understood. In this study, we compared the mammary gland cellular microenvironment influenced/induced by parity and STET alongs...

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Bibliographic Details
Main Authors: Arunkumar Arumugam, Ramadevi Subramani, Sushmita Nandy, Rebecca Lopez, Thiyagarajan Boopalan, Rajkumar Lakshmanaswamy
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
JAK/STAT pathway
Apoptosis
Cell migration
Breast cancer
Cell survival
Pregnancy
Short-term estrogen treatment
Online Access:http://www.karger.com/Article/FullText/363017

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