Shock index, modified shock index, age shock index score, and reverse shock index multiplied by Glasgow Coma Scale predicting clinical outcomes in traumatic brain injury: Evidence from a 10-year analysis in a single center
ObjectivesEarly identification of traumatic brain injury (TBI) patients at a high risk of mortality is very important. This study aimed to compare the predictive accuracy of four scoring systems in TBI, including shock index (SI), modified shock index (MSI), age-adjusted shock index (ASI), and rever...
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| Format: | Article |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.999481/full |
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| author | Po-Chen Lin Po-Chen Lin Chi-Yuan Liu Chi-Yuan Liu I-Shiang Tzeng Tsung-Han Hsieh Chun-Yu Chang Chun-Yu Chang Yueh-Tseng Hou Yueh-Tseng Hou Yu-Long Chen Yu-Long Chen Da-Sen Chien Da-Sen Chien Giou-Teng Yiang Giou-Teng Yiang Meng-Yu Wu Meng-Yu Wu |
| author_facet | Po-Chen Lin Po-Chen Lin Chi-Yuan Liu Chi-Yuan Liu I-Shiang Tzeng Tsung-Han Hsieh Chun-Yu Chang Chun-Yu Chang Yueh-Tseng Hou Yueh-Tseng Hou Yu-Long Chen Yu-Long Chen Da-Sen Chien Da-Sen Chien Giou-Teng Yiang Giou-Teng Yiang Meng-Yu Wu Meng-Yu Wu |
| author_sort | Po-Chen Lin |
| collection | DOAJ |
| description | ObjectivesEarly identification of traumatic brain injury (TBI) patients at a high risk of mortality is very important. This study aimed to compare the predictive accuracy of four scoring systems in TBI, including shock index (SI), modified shock index (MSI), age-adjusted shock index (ASI), and reverse shock index multiplied by the Glasgow Coma Scale (rSIG).Patients and methodsThis is a retrospective analysis of a registry from the Taipei Tzu Chi trauma database. Totally, 1,791 patients with TBI were included. We investigated the accuracy of four major shock indices for TBI mortality. In the subgroup analysis, we also analyzed the effects of age, injury mechanism, underlying diseases, TBI severity, and injury severity.ResultsThe predictive accuracy of rSIG was significantly higher than those of SI, MSI, and ASI in all the patients [area under the receiver operating characteristic curve (AUROC), 0.710 vs. 0.495 vs. 0.527 vs. 0.598], especially in the moderate/severe TBI (AUROC, 0.625 vs. 0.450 vs. 0.476 vs. 0.529) and isolated head injury populations (AUROC 0.689 vs. 0.472 vs. 0.504 vs. 0.587). In the subgroup analysis, the prediction accuracy of mortality of rSIG was better in TBI with major trauma [Injury Severity Score (ISS) ≥ 16], motor vehicle collisions, fall injury, and healthy and cardiovascular disease population. rSIG also had a better prediction effect, as compared to SI, MSI, and ASI, both in the non-geriatric (age < 65 years) and geriatric (age ≥ 65 years).ConclusionrSIG had a better prediction accuracy for mortality in the overall TBI population than SI, MSI, and ASI. Although rSIG have better accuracy than other indices (ROC values indicate poor to moderate accuracy), the further clinical studies are necessary to validate our results. |
| first_indexed | 2024-04-12T06:42:43Z |
| format | Article |
| id | doaj.art-9aa3732a52884acaa035588242a5173b |
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| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-12T06:42:43Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Medicine |
| spelling | doaj.art-9aa3732a52884acaa035588242a5173b2022-12-22T03:43:41ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-11-01910.3389/fmed.2022.999481999481Shock index, modified shock index, age shock index score, and reverse shock index multiplied by Glasgow Coma Scale predicting clinical outcomes in traumatic brain injury: Evidence from a 10-year analysis in a single centerPo-Chen Lin0Po-Chen Lin1Chi-Yuan Liu2Chi-Yuan Liu3I-Shiang Tzeng4Tsung-Han Hsieh5Chun-Yu Chang6Chun-Yu Chang7Yueh-Tseng Hou8Yueh-Tseng Hou9Yu-Long Chen10Yu-Long Chen11Da-Sen Chien12Da-Sen Chien13Giou-Teng Yiang14Giou-Teng Yiang15Meng-Yu Wu16Meng-Yu Wu17Department of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Emergency Medicine, School of Medicine, Tzu Chi University, Hualien City, TaiwanDepartment of Orthopedic Surgery, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Orthopedics, School of Medicine, Tzu Chi University, Hualien City, TaiwanDepartment of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Anesthesiology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Anesthesiology, School of Medicine, Tzu Chi University, Hualien City, TaiwanDepartment of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Emergency Medicine, School of Medicine, Tzu Chi University, Hualien City, TaiwanDepartment of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Emergency Medicine, School of Medicine, Tzu Chi University, Hualien City, TaiwanDepartment of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Emergency Medicine, School of Medicine, Tzu Chi University, Hualien City, TaiwanDepartment of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Emergency Medicine, School of Medicine, Tzu Chi University, Hualien City, TaiwanDepartment of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, TaiwanDepartment of Emergency Medicine, School of Medicine, Tzu Chi University, Hualien City, TaiwanObjectivesEarly identification of traumatic brain injury (TBI) patients at a high risk of mortality is very important. This study aimed to compare the predictive accuracy of four scoring systems in TBI, including shock index (SI), modified shock index (MSI), age-adjusted shock index (ASI), and reverse shock index multiplied by the Glasgow Coma Scale (rSIG).Patients and methodsThis is a retrospective analysis of a registry from the Taipei Tzu Chi trauma database. Totally, 1,791 patients with TBI were included. We investigated the accuracy of four major shock indices for TBI mortality. In the subgroup analysis, we also analyzed the effects of age, injury mechanism, underlying diseases, TBI severity, and injury severity.ResultsThe predictive accuracy of rSIG was significantly higher than those of SI, MSI, and ASI in all the patients [area under the receiver operating characteristic curve (AUROC), 0.710 vs. 0.495 vs. 0.527 vs. 0.598], especially in the moderate/severe TBI (AUROC, 0.625 vs. 0.450 vs. 0.476 vs. 0.529) and isolated head injury populations (AUROC 0.689 vs. 0.472 vs. 0.504 vs. 0.587). In the subgroup analysis, the prediction accuracy of mortality of rSIG was better in TBI with major trauma [Injury Severity Score (ISS) ≥ 16], motor vehicle collisions, fall injury, and healthy and cardiovascular disease population. rSIG also had a better prediction effect, as compared to SI, MSI, and ASI, both in the non-geriatric (age < 65 years) and geriatric (age ≥ 65 years).ConclusionrSIG had a better prediction accuracy for mortality in the overall TBI population than SI, MSI, and ASI. Although rSIG have better accuracy than other indices (ROC values indicate poor to moderate accuracy), the further clinical studies are necessary to validate our results.https://www.frontiersin.org/articles/10.3389/fmed.2022.999481/fullrSIGtraumatic brain injuryshock indexmortalityprediction |
| spellingShingle | Po-Chen Lin Po-Chen Lin Chi-Yuan Liu Chi-Yuan Liu I-Shiang Tzeng Tsung-Han Hsieh Chun-Yu Chang Chun-Yu Chang Yueh-Tseng Hou Yueh-Tseng Hou Yu-Long Chen Yu-Long Chen Da-Sen Chien Da-Sen Chien Giou-Teng Yiang Giou-Teng Yiang Meng-Yu Wu Meng-Yu Wu Shock index, modified shock index, age shock index score, and reverse shock index multiplied by Glasgow Coma Scale predicting clinical outcomes in traumatic brain injury: Evidence from a 10-year analysis in a single center Frontiers in Medicine rSIG traumatic brain injury shock index mortality prediction |
| title | Shock index, modified shock index, age shock index score, and reverse shock index multiplied by Glasgow Coma Scale predicting clinical outcomes in traumatic brain injury: Evidence from a 10-year analysis in a single center |
| title_full | Shock index, modified shock index, age shock index score, and reverse shock index multiplied by Glasgow Coma Scale predicting clinical outcomes in traumatic brain injury: Evidence from a 10-year analysis in a single center |
| title_fullStr | Shock index, modified shock index, age shock index score, and reverse shock index multiplied by Glasgow Coma Scale predicting clinical outcomes in traumatic brain injury: Evidence from a 10-year analysis in a single center |
| title_full_unstemmed | Shock index, modified shock index, age shock index score, and reverse shock index multiplied by Glasgow Coma Scale predicting clinical outcomes in traumatic brain injury: Evidence from a 10-year analysis in a single center |
| title_short | Shock index, modified shock index, age shock index score, and reverse shock index multiplied by Glasgow Coma Scale predicting clinical outcomes in traumatic brain injury: Evidence from a 10-year analysis in a single center |
| title_sort | shock index modified shock index age shock index score and reverse shock index multiplied by glasgow coma scale predicting clinical outcomes in traumatic brain injury evidence from a 10 year analysis in a single center |
| topic | rSIG traumatic brain injury shock index mortality prediction |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.999481/full |
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