Blueberry muffin baby syndrome. A critical primary sign of systemic disease

Blueberry muffin baby syndrome is a rare and non-specific clinical presentation in newborns, characterized by the presence of widespread, maculopapular lesions of blue-red or violaceous colour and cohesive consistency [1]. The term “blueberry muffin baby” was initially coined to describe the skin ma...

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Main Authors: Katarzyna Kaleta, Agata Kłosowicz, Natalia Juśko, Monika Kapińska-Mrowiecka
Format: Article
Language:English
Published: Termedia Publishing House 2022-05-01
Series:Advances in Dermatology and Allergology
Online Access:https://www.termedia.pl/Blueberry-muffin-baby-syndrome-A-critical-primary-sign-r-nof-systemic-disease,7,46956,1,1.html
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author Katarzyna Kaleta
Agata Kłosowicz
Natalia Juśko
Monika Kapińska-Mrowiecka
author_facet Katarzyna Kaleta
Agata Kłosowicz
Natalia Juśko
Monika Kapińska-Mrowiecka
author_sort Katarzyna Kaleta
collection DOAJ
description Blueberry muffin baby syndrome is a rare and non-specific clinical presentation in newborns, characterized by the presence of widespread, maculopapular lesions of blue-red or violaceous colour and cohesive consistency [1]. The term “blueberry muffin baby” was initially coined to describe the skin manifestations of congenital rubella during the American epidemic in the 1960s [2, 3]. The presence of skin lesions is secondary to extramedullary hematopoiesis, which can result from intrauterine viral infections (TORCH syndrome), hematologic dyscrasias (twin-to-twin transfusion syndrome, hereditary spherocytosis, haemolytic disease of the newborn) or neoplasms (mastocytosis, histiocytosis, neuroblastoma, rhabdomyosarcoma, leukaemia) [1, 3].
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spelling doaj.art-9aa44f126b094b50b5a5dfe3b79941e92022-12-22T04:31:18ZengTermedia Publishing HouseAdvances in Dermatology and Allergology1642-395X2299-00462022-05-0139241842010.5114/ada.2022.11589546956Blueberry muffin baby syndrome. A critical primary sign of systemic diseaseKatarzyna KaletaAgata KłosowiczNatalia JuśkoMonika Kapińska-MrowieckaBlueberry muffin baby syndrome is a rare and non-specific clinical presentation in newborns, characterized by the presence of widespread, maculopapular lesions of blue-red or violaceous colour and cohesive consistency [1]. The term “blueberry muffin baby” was initially coined to describe the skin manifestations of congenital rubella during the American epidemic in the 1960s [2, 3]. The presence of skin lesions is secondary to extramedullary hematopoiesis, which can result from intrauterine viral infections (TORCH syndrome), hematologic dyscrasias (twin-to-twin transfusion syndrome, hereditary spherocytosis, haemolytic disease of the newborn) or neoplasms (mastocytosis, histiocytosis, neuroblastoma, rhabdomyosarcoma, leukaemia) [1, 3].https://www.termedia.pl/Blueberry-muffin-baby-syndrome-A-critical-primary-sign-r-nof-systemic-disease,7,46956,1,1.html
spellingShingle Katarzyna Kaleta
Agata Kłosowicz
Natalia Juśko
Monika Kapińska-Mrowiecka
Blueberry muffin baby syndrome. A critical primary sign of systemic disease
Advances in Dermatology and Allergology
title Blueberry muffin baby syndrome. A critical primary sign of systemic disease
title_full Blueberry muffin baby syndrome. A critical primary sign of systemic disease
title_fullStr Blueberry muffin baby syndrome. A critical primary sign of systemic disease
title_full_unstemmed Blueberry muffin baby syndrome. A critical primary sign of systemic disease
title_short Blueberry muffin baby syndrome. A critical primary sign of systemic disease
title_sort blueberry muffin baby syndrome a critical primary sign of systemic disease
url https://www.termedia.pl/Blueberry-muffin-baby-syndrome-A-critical-primary-sign-r-nof-systemic-disease,7,46956,1,1.html
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