Presumptive complicating Clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo-obstruction
Clostridium paraputrificum is a member of the commensal flora of the gastrointestinal tract and skin. Despite being linked with cases of severe invasive infection, this organism is an uncommon pathogen in humans. Here, we report a case of undiagnosed ulcerative colitis in which the presentation was...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250922002803 |
| _version_ | 1797869768988950528 |
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| author | Masahiko Kaneko Chie Moriyama Yuya Masuda Hiroshi Sawachika Hisaharu Shikata Shoichi Matsukage |
| author_facet | Masahiko Kaneko Chie Moriyama Yuya Masuda Hiroshi Sawachika Hisaharu Shikata Shoichi Matsukage |
| author_sort | Masahiko Kaneko |
| collection | DOAJ |
| description | Clostridium paraputrificum is a member of the commensal flora of the gastrointestinal tract and skin. Despite being linked with cases of severe invasive infection, this organism is an uncommon pathogen in humans. Here, we report a case of undiagnosed ulcerative colitis in which the presentation was one of presumptive complicating C. paraputrificum bacteremia and, later, acute colonic pseudo-obstruction. The patient was an elderly male with prostate cancer who was admitted in a state of shock secondary to suspected septicemia from an abdominal source. Only one of two sets of anaerobic blood cultures were positive for C. paraputrificum. Endoscopic and pathological investigations revealed proctitis consistent with ulcerative colitis. The patient’s abdominal manifestations worsened, and abdominal imaging demonstrated de novo massive colonic dilatation without any apparent mechanical obstruction. We speculated that C. paraputrificum bacteremia caused by undiagnosed ulcerative colitis had created ideal conditions for acute colonic pseudo-obstruction. This case demonstrates that C. paraputrificum bacteremia can be associated with latent severe gastrointestinal pathologies, indicating the need to investigate any abdominal source of infection, even if only a single blood culture is positive. |
| first_indexed | 2024-04-10T00:17:25Z |
| format | Article |
| id | doaj.art-9aa9b7606c224b2398bc999793cbbff2 |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-04-10T00:17:25Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-9aa9b7606c224b2398bc999793cbbff22023-03-16T05:04:21ZengElsevierIDCases2214-25092023-01-0131e01652Presumptive complicating Clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo-obstructionMasahiko Kaneko0Chie Moriyama1Yuya Masuda2Hiroshi Sawachika3Hisaharu Shikata4Shoichi Matsukage5Department of Hematology, Uwajima City Hospital, 1-1 Goten-machi, Uwajima City, Ehime 798-8510, Japan; Correspondence to: Department of Internal Medicine, Uwajima City Hospital, 1-1 Goten-machi, Uwajima City, Ehime 798-8510, Japan.Clinical Laboratory Department, Uwajima City Hospital, 1-1 Goten-machi, Uwajima City, Ehime 798-8510, JapanDepartment of Hematology, Uwajima City Hospital, 1-1 Goten-machi, Uwajima City, Ehime 798-8510, JapanDepartment of Hematology, Uwajima City Hospital, 1-1 Goten-machi, Uwajima City, Ehime 798-8510, JapanDepartment of Hematology, Uwajima City Hospital, 1-1 Goten-machi, Uwajima City, Ehime 798-8510, JapanDepartment of Pathology, Uwajima City Hospital, 1-1 Goten-machi, Uwajima City, Ehime 798-8510, JapanClostridium paraputrificum is a member of the commensal flora of the gastrointestinal tract and skin. Despite being linked with cases of severe invasive infection, this organism is an uncommon pathogen in humans. Here, we report a case of undiagnosed ulcerative colitis in which the presentation was one of presumptive complicating C. paraputrificum bacteremia and, later, acute colonic pseudo-obstruction. The patient was an elderly male with prostate cancer who was admitted in a state of shock secondary to suspected septicemia from an abdominal source. Only one of two sets of anaerobic blood cultures were positive for C. paraputrificum. Endoscopic and pathological investigations revealed proctitis consistent with ulcerative colitis. The patient’s abdominal manifestations worsened, and abdominal imaging demonstrated de novo massive colonic dilatation without any apparent mechanical obstruction. We speculated that C. paraputrificum bacteremia caused by undiagnosed ulcerative colitis had created ideal conditions for acute colonic pseudo-obstruction. This case demonstrates that C. paraputrificum bacteremia can be associated with latent severe gastrointestinal pathologies, indicating the need to investigate any abdominal source of infection, even if only a single blood culture is positive.http://www.sciencedirect.com/science/article/pii/S2214250922002803Clostridium paraputrificumBacteremiaUlcerative colitisAcute colonic pseudoobstruction |
| spellingShingle | Masahiko Kaneko Chie Moriyama Yuya Masuda Hiroshi Sawachika Hisaharu Shikata Shoichi Matsukage Presumptive complicating Clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo-obstruction IDCases Clostridium paraputrificum Bacteremia Ulcerative colitis Acute colonic pseudoobstruction |
| title | Presumptive complicating Clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo-obstruction |
| title_full | Presumptive complicating Clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo-obstruction |
| title_fullStr | Presumptive complicating Clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo-obstruction |
| title_full_unstemmed | Presumptive complicating Clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo-obstruction |
| title_short | Presumptive complicating Clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo-obstruction |
| title_sort | presumptive complicating clostridium paraputrificum bacteremia as a presenting manifestation in a patient with undiagnosed ulcerative colitis followed by acute colonic pseudo obstruction |
| topic | Clostridium paraputrificum Bacteremia Ulcerative colitis Acute colonic pseudoobstruction |
| url | http://www.sciencedirect.com/science/article/pii/S2214250922002803 |
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