Tetrahydrocurcumin Ameliorates Kidney Injury and High Systolic Blood Pressure in High-Fat Diet-Induced Type 2 Diabetic Mice

Tetrahydrocurcumin Ameliorates Kidney Injury and High Systolic Blood Pressure in High-Fat Diet-Induced Type 2 Diabetic Mice

Background Activation of the intrarenal renin-angiotensin system (RAS) is implicated in the pathogenesis of kidney injury and hypertension. We aimed to investigate the protective effect of tetrahydrocurcumin (THU) on intrarenal RAS expression, kidney injury, and systolic blood pressure (SBP) in high...

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Bibliographic Details
Main Authors: Weerapon Sangartit, Kyung Bong Ha, Eun Soo Lee, Hong Min Kim, Upa Kukongviriyapan, Eun Young Lee, Choon Hee Chung
Format: Article
Language:English
Published: Korean Endocrine Society 2021-08-01
Series:Endocrinology and Metabolism
Subjects:
diabetic nephropathies
renin-angiotensin system
hypertension
tetrahydrocurcumin
curcumin
Online Access:http://www.e-enm.org/upload/pdf/enm-2021-988.pdf

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