A Non-Framework Multilevel Surgery May Reduce Mean Heart Rate in Patients with Very Severe Obstructive Apnea Having Confined Retroglossal Space and Framework
An elevated mean heart rate in untreated patients of obstructive sleep apnea (OSA) may lead to a higher risk of mortality and the development of various cardiovascular diseases. The elevation may positively relate to the severity of OSA and present in both wakefulness and sleep. A reduction in heart...
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| Format: | Article |
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MDPI AG
2020-11-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/10/22/8094 |
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| author | Ethan I. Huang Shu-Yi Huang Yu-Ching Lin Chieh-Mo Lin Chin-Kuo Lin Ying-Chih Huang Jian-An Su |
| author_facet | Ethan I. Huang Shu-Yi Huang Yu-Ching Lin Chieh-Mo Lin Chin-Kuo Lin Ying-Chih Huang Jian-An Su |
| author_sort | Ethan I. Huang |
| collection | DOAJ |
| description | An elevated mean heart rate in untreated patients of obstructive sleep apnea (OSA) may lead to a higher risk of mortality and the development of various cardiovascular diseases. The elevation may positively relate to the severity of OSA and present in both wakefulness and sleep. A reduction in heart rate has been presented in reports of treating OSA patients with continuous positive airway pressure (CPAP). However, patients with very severe OSA may refuse use of CPAP devices and advocated surgeries, such as direct skeletal surgery or tracheostomy. It is unclear whether the non-framework multilevel surgery we reported previously can overcome the unfavorable anatomy and reduce mean heart rate, which serves as a risk factor of mortality. Here, we show that multilevel surgery reduced the mean heart rate from 68.6 to 62.7 with a mean reduction of 5.9 beats/min. The results suggest that the surgery may reduce the risk of consequences and mortality associated with an elevated mean heart rate, such as various cardiovascular diseases. We disclose these findings, along with the variations and possible risks to our future patients with very severe OSA who refuse or cannot use a CPAP device or reject direct skeletal surgery. |
| first_indexed | 2024-03-10T14:49:56Z |
| format | Article |
| id | doaj.art-9aacf1f57b61445b9ad993d1d15760b7 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T14:49:56Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-9aacf1f57b61445b9ad993d1d15760b72023-11-20T21:03:56ZengMDPI AGApplied Sciences2076-34172020-11-011022809410.3390/app10228094A Non-Framework Multilevel Surgery May Reduce Mean Heart Rate in Patients with Very Severe Obstructive Apnea Having Confined Retroglossal Space and FrameworkEthan I. Huang0Shu-Yi Huang1Yu-Ching Lin2Chieh-Mo Lin3Chin-Kuo Lin4Ying-Chih Huang5Jian-An Su6Department of Otolaryngology, Chang Gung Memorial Hospital, Chiayi 61363, TaiwanSleep Center of Chang Gung Memorial Hospital, Chiayi 61363, TaiwanSleep Center of Chang Gung Memorial Hospital, Chiayi 61363, TaiwanDivision of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Chiayi 61363, TaiwanDivision of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Chiayi 61363, TaiwanDepartment of Neurology, Chang Gung Memorial Hospital, Chiayi 61363, TaiwanDepartment of Psychiatry, Chang Gung Memorial Hospital, Chiayi 61363, TaiwanAn elevated mean heart rate in untreated patients of obstructive sleep apnea (OSA) may lead to a higher risk of mortality and the development of various cardiovascular diseases. The elevation may positively relate to the severity of OSA and present in both wakefulness and sleep. A reduction in heart rate has been presented in reports of treating OSA patients with continuous positive airway pressure (CPAP). However, patients with very severe OSA may refuse use of CPAP devices and advocated surgeries, such as direct skeletal surgery or tracheostomy. It is unclear whether the non-framework multilevel surgery we reported previously can overcome the unfavorable anatomy and reduce mean heart rate, which serves as a risk factor of mortality. Here, we show that multilevel surgery reduced the mean heart rate from 68.6 to 62.7 with a mean reduction of 5.9 beats/min. The results suggest that the surgery may reduce the risk of consequences and mortality associated with an elevated mean heart rate, such as various cardiovascular diseases. We disclose these findings, along with the variations and possible risks to our future patients with very severe OSA who refuse or cannot use a CPAP device or reject direct skeletal surgery.https://www.mdpi.com/2076-3417/10/22/8094palatoplastyone-stageretropharynxhypertensionmaxillomandibular advancementcomorbidity |
| spellingShingle | Ethan I. Huang Shu-Yi Huang Yu-Ching Lin Chieh-Mo Lin Chin-Kuo Lin Ying-Chih Huang Jian-An Su A Non-Framework Multilevel Surgery May Reduce Mean Heart Rate in Patients with Very Severe Obstructive Apnea Having Confined Retroglossal Space and Framework Applied Sciences palatoplasty one-stage retropharynx hypertension maxillomandibular advancement comorbidity |
| title | A Non-Framework Multilevel Surgery May Reduce Mean Heart Rate in Patients with Very Severe Obstructive Apnea Having Confined Retroglossal Space and Framework |
| title_full | A Non-Framework Multilevel Surgery May Reduce Mean Heart Rate in Patients with Very Severe Obstructive Apnea Having Confined Retroglossal Space and Framework |
| title_fullStr | A Non-Framework Multilevel Surgery May Reduce Mean Heart Rate in Patients with Very Severe Obstructive Apnea Having Confined Retroglossal Space and Framework |
| title_full_unstemmed | A Non-Framework Multilevel Surgery May Reduce Mean Heart Rate in Patients with Very Severe Obstructive Apnea Having Confined Retroglossal Space and Framework |
| title_short | A Non-Framework Multilevel Surgery May Reduce Mean Heart Rate in Patients with Very Severe Obstructive Apnea Having Confined Retroglossal Space and Framework |
| title_sort | non framework multilevel surgery may reduce mean heart rate in patients with very severe obstructive apnea having confined retroglossal space and framework |
| topic | palatoplasty one-stage retropharynx hypertension maxillomandibular advancement comorbidity |
| url | https://www.mdpi.com/2076-3417/10/22/8094 |
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