Expansion of mouse castration-resistant intermediate prostate stem cells in vitro

Expansion of mouse castration-resistant intermediate prostate stem cells in vitro

Abstract Background Most castration-resistant prostate cancers (CRPCs) have a luminal phenotype with high androgen receptor (AR) and prostate-specific antigen (PSA) expression. Currently, it is difficult to culture castration-resistant luminal cells with AR and PSA expression. Methods We formulated...

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Bibliographic Details
Main Authors: Yalan Xu, Jie Mu, Zhixia Zhou, Yu Leng, Yali Yu, Xiuyue Song, Aihua Liu, Hai Zhu, Jing Li, Dong Wang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
castration-resistant prostate cancer
Stem cell
Intermediate cell
Androgen receptor
Prostate-specific antigen
Androgen deprivation
Online Access:https://doi.org/10.1186/s13287-022-02978-x

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