A frameshift variant in the SIRPB1 gene confers susceptibility to Crohn’s disease in a Chinese population

A frameshift variant in the SIRPB1 gene confers susceptibility to Crohn’s disease in a Chinese population

Background: Crohn’s disease (CD), a chronic gastrointestinal inflammatory disease, is increasing in China. With a focus on Han Chinese families with CD, the aim of this study was to find genetic variations that increase CD susceptibility by genome sequencing, genetic association, expression, and fun...

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Bibliographic Details
Main Authors: Jian Tang, Xingyang Wan, JunXiao Zhang, Na Diao, Caibin Zhang, Xiang Gao, Donglin Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Genetics
Subjects:
Crohn ‘s disease
han Chinese patients
gene susceptibility
whole gene sequencing
SIRPB1
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1130529/full

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