BT3 molecules ligation enhances the proinflammatory responses of human monocytes and monocyte-derived dendritic cells

BT3 molecules ligation enhances the proinflammatory responses of human monocytes and monocyte-derived dendritic cells

BT3, a new family of immunoreceptors, belongs to the extended B7 family. BT3 are expressed on the surface of resting and activated monocytes and monocytes-derived dendritic cells (iDC). We show that BT3 cross-linking, in the absence of other survival factors, provides a survival signal for monocytes...

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Bibliographic Details
Main Authors: R. Simone, A. Rabellino, G. Icardi, M. Bagnasco, G. Pesce, D. Olive, D. Saverino
Format: Article
Language:English
Published: PAGEPress Publications 2011-01-01
Series:Journal of Biological Research
Subjects:
BT3, B7 family, monocytes, dendritic cells, Toll-like receptors
Online Access:http://www.pagepressjournals.org/index.php/jbr/article/view/4664

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