Honey and its nutritional and anti-inflammatory value

Abstract Inflammation is the main key role in developing chronic diseases including cancer, cardiovascular diseases, diabetes, arthritis, and neurodegenerative diseases which possess a huge challenge for treatment. With massively compelling evidence of the role played by nutritional modulation in pr...

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Main Authors: Yazan Ranneh, Abdah Md Akim, Hasiah Ab. Hamid, Huzwah Khazaai, Abdulmannan Fadel, Zainul Amiruddin Zakaria, Mohammed Albujja, Mohd Fadzelly Abu Bakar
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-020-03170-5
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author Yazan Ranneh
Abdah Md Akim
Hasiah Ab. Hamid
Huzwah Khazaai
Abdulmannan Fadel
Zainul Amiruddin Zakaria
Mohammed Albujja
Mohd Fadzelly Abu Bakar
author_facet Yazan Ranneh
Abdah Md Akim
Hasiah Ab. Hamid
Huzwah Khazaai
Abdulmannan Fadel
Zainul Amiruddin Zakaria
Mohammed Albujja
Mohd Fadzelly Abu Bakar
author_sort Yazan Ranneh
collection DOAJ
description Abstract Inflammation is the main key role in developing chronic diseases including cancer, cardiovascular diseases, diabetes, arthritis, and neurodegenerative diseases which possess a huge challenge for treatment. With massively compelling evidence of the role played by nutritional modulation in preventing inflammation-related diseases, there is a growing interest into the search for natural functional foods with therapeutic and preventive actions. Honey, a nutritional healthy product, is produced mainly by two types of bees: honeybee and stingless bee. Since both types of honey possess distinctive phenolic and flavonoid compounds, there is recently an intensive interest in their biological and clinical actions against inflammation-mediated chronic diseases. This review shed the light specifically on the bioavailability and bioaccessibility of honey polyphenols and highlight their roles in targeting inflammatory pathways in gastrointestinal tract disorders, edema, cancer, metabolic and cardiovascular diseases and gut microbiota.
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spelling doaj.art-9ab15147b6c34e77bc7db68f3e44035c2022-12-21T20:48:17ZengBMCBMC Complementary Medicine and Therapies2662-76712021-01-0121111710.1186/s12906-020-03170-5Honey and its nutritional and anti-inflammatory valueYazan Ranneh0Abdah Md Akim1Hasiah Ab. Hamid2Huzwah Khazaai3Abdulmannan Fadel4Zainul Amiruddin Zakaria5Mohammed Albujja6Mohd Fadzelly Abu Bakar7Department of Technology and Natural Resources, Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn MalaysiaDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra MalaysiaDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra MalaysiaDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra MalaysiaSport and Exercises Sciences School, Faculty of Science, Liverpool John Moores UniversityDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra MalaysiaDepartment of Forensic Biology, Faculty of Forensic Sciences, Naif Arab University of Security SciencesDepartment of Technology and Natural Resources, Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn MalaysiaAbstract Inflammation is the main key role in developing chronic diseases including cancer, cardiovascular diseases, diabetes, arthritis, and neurodegenerative diseases which possess a huge challenge for treatment. With massively compelling evidence of the role played by nutritional modulation in preventing inflammation-related diseases, there is a growing interest into the search for natural functional foods with therapeutic and preventive actions. Honey, a nutritional healthy product, is produced mainly by two types of bees: honeybee and stingless bee. Since both types of honey possess distinctive phenolic and flavonoid compounds, there is recently an intensive interest in their biological and clinical actions against inflammation-mediated chronic diseases. This review shed the light specifically on the bioavailability and bioaccessibility of honey polyphenols and highlight their roles in targeting inflammatory pathways in gastrointestinal tract disorders, edema, cancer, metabolic and cardiovascular diseases and gut microbiota.https://doi.org/10.1186/s12906-020-03170-5HoneyChronic inflammationBioavailabilityBioaccessibilityBioactive compounds
spellingShingle Yazan Ranneh
Abdah Md Akim
Hasiah Ab. Hamid
Huzwah Khazaai
Abdulmannan Fadel
Zainul Amiruddin Zakaria
Mohammed Albujja
Mohd Fadzelly Abu Bakar
Honey and its nutritional and anti-inflammatory value
BMC Complementary Medicine and Therapies
Honey
Chronic inflammation
Bioavailability
Bioaccessibility
Bioactive compounds
title Honey and its nutritional and anti-inflammatory value
title_full Honey and its nutritional and anti-inflammatory value
title_fullStr Honey and its nutritional and anti-inflammatory value
title_full_unstemmed Honey and its nutritional and anti-inflammatory value
title_short Honey and its nutritional and anti-inflammatory value
title_sort honey and its nutritional and anti inflammatory value
topic Honey
Chronic inflammation
Bioavailability
Bioaccessibility
Bioactive compounds
url https://doi.org/10.1186/s12906-020-03170-5
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AT hasiahabhamid honeyanditsnutritionalandantiinflammatoryvalue
AT huzwahkhazaai honeyanditsnutritionalandantiinflammatoryvalue
AT abdulmannanfadel honeyanditsnutritionalandantiinflammatoryvalue
AT zainulamiruddinzakaria honeyanditsnutritionalandantiinflammatoryvalue
AT mohammedalbujja honeyanditsnutritionalandantiinflammatoryvalue
AT mohdfadzellyabubakar honeyanditsnutritionalandantiinflammatoryvalue