Bio-Nanohybrid Gelatin/Quantum Dots for Cellular Imaging and Biosensing Applications

The bio-nanohybrid gelatin protein/cadmium sulfide (Gel/CdS) quantum dots (QDs) have been designed via a facile one-pot strategy. The amino acids group of gelatin chelate Cd<sup>2+</sup> and grow CdS QDs without any agglomeration. The <sup>1</sup>H NMR spectra indicate that d...

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Bibliographic Details
Main Authors: Sangram Keshari Samal, Stefaan Soenen, Dario Puppi, Karolien De Wael, Sanghamitra Pati, Stefaan De Smedt, Kevin Braeckmans, Peter Dubruel
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/19/11867
Description
Summary:The bio-nanohybrid gelatin protein/cadmium sulfide (Gel/CdS) quantum dots (QDs) have been designed via a facile one-pot strategy. The amino acids group of gelatin chelate Cd<sup>2+</sup> and grow CdS QDs without any agglomeration. The <sup>1</sup>H NMR spectra indicate that during the above process there are no alterations of the gelatin protein structure conformation and chemical functionalities. The prepared Gel/CdS QDs were characterized and their potential as a system for cellular imaging and the electrochemical sensor for hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) detection applications were investigated. The obtained results demonstrate that the developed Gel/CdS QDs system could offer a simple and convenient operating strategy both for the class of contrast agents for cell labeling and electrochemical sensors purposes.
ISSN:1661-6596
1422-0067