Suppression of Vps13 adaptor protein mutants reveals a central role for PI4P in regulating prospore membrane extension.
Vps13 family proteins are proposed to function in bulk lipid transfer between membranes, but little is known about their regulation. During sporulation of Saccharomyces cerevisiae, Vps13 localizes to the prospore membrane (PSM) via the Spo71-Spo73 adaptor complex. We previously reported that loss of...
Main Authors: | Tsuyoshi S Nakamura, Yasuyuki Suda, Kenji Muneshige, Yuji Fujieda, Yuuya Okumura, Ichiro Inoue, Takayuki Tanaka, Tetsuo Takahashi, Hideki Nakanishi, Xiao-Dong Gao, Yasushi Okada, Aaron M Neiman, Hiroyuki Tachikawa |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-08-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1009727 |
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