Genetic diversity and Kdr mutations of natural Aedes (Stegomyia) aegypti (Diptera: Culicidae) populations of Brazil
ABSTRACT Aedes (Stegomyia) aegypti is an important vector of dengue, yellow fever, chikungunya and Zika virus. It is well known that resistance monitoring and genetic diversity data help designing the vector control programs. This study aimed to evaluate resistance to pyrethroids (PYs) through the f...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Entomologia
2023-11-01
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| Series: | Revista Brasileira de Entomologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262023000300207&tlng=en |
| _version_ | 1797635123168935936 |
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| author | Monique Ane da Luz Ferreira Oscar Alexander Aguirre-Obando Adriana Lacerda Twerdochlib Angela Maria Palacio-Cortés Mário Antônio Navarro-Silva |
| author_facet | Monique Ane da Luz Ferreira Oscar Alexander Aguirre-Obando Adriana Lacerda Twerdochlib Angela Maria Palacio-Cortés Mário Antônio Navarro-Silva |
| author_sort | Monique Ane da Luz Ferreira |
| collection | DOAJ |
| description | ABSTRACT Aedes (Stegomyia) aegypti is an important vector of dengue, yellow fever, chikungunya and Zika virus. It is well known that resistance monitoring and genetic diversity data help designing the vector control programs. This study aimed to evaluate resistance to pyrethroids (PYs) through the frequency of kdr mutations Val1016IIe and F1534C, and the genetic variation of the mitochondrial gene ND4 in six natural populations of A. aegypti from Paraná - Brazil. Adults were obtained from eggs collected from Alvorada do Sul, Marilena, Maringá, Nova Londrina, Paranavaí and São Carlos do Ivaí. From these adults, 345 were used to identify the 1016 and 1534 sites, and 120 were used to perform the ND4 gene analysis. The studied populations from Paraná showed PYs resistance, low gene flow and genetic diversity. Additionally, a relationship was observed among the haplotypes of populations from the Amazon and Southeastern Brazil, Peru, Mexico, and North America. |
| first_indexed | 2024-03-11T12:16:53Z |
| format | Article |
| id | doaj.art-9ab64bcfdd46490aa534ca7097130767 |
| institution | Directory Open Access Journal |
| issn | 1806-9665 |
| language | English |
| last_indexed | 2024-03-11T12:16:53Z |
| publishDate | 2023-11-01 |
| publisher | Sociedade Brasileira de Entomologia |
| record_format | Article |
| series | Revista Brasileira de Entomologia |
| spelling | doaj.art-9ab64bcfdd46490aa534ca70971307672023-11-07T07:42:41ZengSociedade Brasileira de EntomologiaRevista Brasileira de Entomologia1806-96652023-11-0167310.1590/1806-9665-rbent-2023-0047Genetic diversity and Kdr mutations of natural Aedes (Stegomyia) aegypti (Diptera: Culicidae) populations of BrazilMonique Ane da Luz FerreiraOscar Alexander Aguirre-Obandohttps://orcid.org/0000-0003-2480-7004Adriana Lacerda TwerdochlibAngela Maria Palacio-Cortéshttps://orcid.org/0000-0001-7437-8880Mário Antônio Navarro-Silvahttps://orcid.org/0000-0002-9762-632XABSTRACT Aedes (Stegomyia) aegypti is an important vector of dengue, yellow fever, chikungunya and Zika virus. It is well known that resistance monitoring and genetic diversity data help designing the vector control programs. This study aimed to evaluate resistance to pyrethroids (PYs) through the frequency of kdr mutations Val1016IIe and F1534C, and the genetic variation of the mitochondrial gene ND4 in six natural populations of A. aegypti from Paraná - Brazil. Adults were obtained from eggs collected from Alvorada do Sul, Marilena, Maringá, Nova Londrina, Paranavaí and São Carlos do Ivaí. From these adults, 345 were used to identify the 1016 and 1534 sites, and 120 were used to perform the ND4 gene analysis. The studied populations from Paraná showed PYs resistance, low gene flow and genetic diversity. Additionally, a relationship was observed among the haplotypes of populations from the Amazon and Southeastern Brazil, Peru, Mexico, and North America.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262023000300207&tlng=enPyrethroid resistanceVector controlKdr mutationsGenetic diversity |
| spellingShingle | Monique Ane da Luz Ferreira Oscar Alexander Aguirre-Obando Adriana Lacerda Twerdochlib Angela Maria Palacio-Cortés Mário Antônio Navarro-Silva Genetic diversity and Kdr mutations of natural Aedes (Stegomyia) aegypti (Diptera: Culicidae) populations of Brazil Revista Brasileira de Entomologia Pyrethroid resistance Vector control Kdr mutations Genetic diversity |
| title | Genetic diversity and Kdr mutations of natural Aedes (Stegomyia) aegypti (Diptera: Culicidae) populations of Brazil |
| title_full | Genetic diversity and Kdr mutations of natural Aedes (Stegomyia) aegypti (Diptera: Culicidae) populations of Brazil |
| title_fullStr | Genetic diversity and Kdr mutations of natural Aedes (Stegomyia) aegypti (Diptera: Culicidae) populations of Brazil |
| title_full_unstemmed | Genetic diversity and Kdr mutations of natural Aedes (Stegomyia) aegypti (Diptera: Culicidae) populations of Brazil |
| title_short | Genetic diversity and Kdr mutations of natural Aedes (Stegomyia) aegypti (Diptera: Culicidae) populations of Brazil |
| title_sort | genetic diversity and kdr mutations of natural aedes stegomyia aegypti diptera culicidae populations of brazil |
| topic | Pyrethroid resistance Vector control Kdr mutations Genetic diversity |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262023000300207&tlng=en |
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