Cocaine-Induced Time-Dependent Alterations in Cytochrome P450 and Liver Function
Cytochrome P450 is responsible for the metabolism of endogenous substrates, drugs and substances of abuse. The brain and nervous system regulate liver cytochrome P450 via neuroendocrine mechanisms, as shown in rodents. Cocaine exerts its addictive effects through the dopaminergic system, the functio...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/2/1632 |