TORASEMIDE SAFETY IN COMPLEX THERAPY OF CHRONIC CARDIAC INSUFFICIENCY: RESULTS OF RANDOMIZED CROSS STUDY
In therapy of patients with chronic cardiac insufficiency we must use obligatory drugs as angiotensin-converting enzyme inhibitors (ACE inhibitors)/sartans, β-antagonists and mineral- corticoid receptor antagonists (MCRA). As is known, ACE inhibitors and MCRA can lead to potassium retention in the h...
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2016-12-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/1367 |
| _version_ | 1797841780060717056 |
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| author | E. E. AVERIN |
| author_facet | E. E. AVERIN |
| author_sort | E. E. AVERIN |
| collection | DOAJ |
| description | In therapy of patients with chronic cardiac insufficiency we must use obligatory drugs as angiotensin-converting enzyme inhibitors (ACE inhibitors)/sartans, β-antagonists and mineral- corticoid receptor antagonists (MCRA). As is known, ACE inhibitors and MCRA can lead to potassium retention in the human body [1, 2]. Fear of hyperkalemia development in patients might increase due to the fact that the majority of patients are older than 60 and they might have disturbances of the kidney function. Nevertheless, data provided by R. Pisoni [3], testify about not frequent development of hyperkalemia in patients with chronic renal disease and use in therapy of spironolactone. Results of the study RALES (Randomized Aldactone Evaluation Study) [4] showed that inclusion in the therapy of spironactone had advantages compared to therapy without pironolactone in patients with cardiac insufficiency and reduced GFR. |
| first_indexed | 2024-04-09T16:36:23Z |
| format | Article |
| id | doaj.art-9abcfe928bc4475ba23e0f0483888f3d |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:36:23Z |
| publishDate | 2016-12-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-9abcfe928bc4475ba23e0f0483888f3d2023-04-23T06:56:53ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902016-12-01013818410.21518/2079-701X-2016-13-81-841365TORASEMIDE SAFETY IN COMPLEX THERAPY OF CHRONIC CARDIAC INSUFFICIENCY: RESULTS OF RANDOMIZED CROSS STUDYE. E. AVERIN0Pirogov Russian National Research University of the Ministry of Health of RussiaIn therapy of patients with chronic cardiac insufficiency we must use obligatory drugs as angiotensin-converting enzyme inhibitors (ACE inhibitors)/sartans, β-antagonists and mineral- corticoid receptor antagonists (MCRA). As is known, ACE inhibitors and MCRA can lead to potassium retention in the human body [1, 2]. Fear of hyperkalemia development in patients might increase due to the fact that the majority of patients are older than 60 and they might have disturbances of the kidney function. Nevertheless, data provided by R. Pisoni [3], testify about not frequent development of hyperkalemia in patients with chronic renal disease and use in therapy of spironolactone. Results of the study RALES (Randomized Aldactone Evaluation Study) [4] showed that inclusion in the therapy of spironactone had advantages compared to therapy without pironolactone in patients with cardiac insufficiency and reduced GFR.https://www.med-sovet.pro/jour/article/view/1367chronic cardiac insufficiencytorasemidefurosemide |
| spellingShingle | E. E. AVERIN TORASEMIDE SAFETY IN COMPLEX THERAPY OF CHRONIC CARDIAC INSUFFICIENCY: RESULTS OF RANDOMIZED CROSS STUDY Медицинский совет chronic cardiac insufficiency torasemide furosemide |
| title | TORASEMIDE SAFETY IN COMPLEX THERAPY OF CHRONIC CARDIAC INSUFFICIENCY: RESULTS OF RANDOMIZED CROSS STUDY |
| title_full | TORASEMIDE SAFETY IN COMPLEX THERAPY OF CHRONIC CARDIAC INSUFFICIENCY: RESULTS OF RANDOMIZED CROSS STUDY |
| title_fullStr | TORASEMIDE SAFETY IN COMPLEX THERAPY OF CHRONIC CARDIAC INSUFFICIENCY: RESULTS OF RANDOMIZED CROSS STUDY |
| title_full_unstemmed | TORASEMIDE SAFETY IN COMPLEX THERAPY OF CHRONIC CARDIAC INSUFFICIENCY: RESULTS OF RANDOMIZED CROSS STUDY |
| title_short | TORASEMIDE SAFETY IN COMPLEX THERAPY OF CHRONIC CARDIAC INSUFFICIENCY: RESULTS OF RANDOMIZED CROSS STUDY |
| title_sort | torasemide safety in complex therapy of chronic cardiac insufficiency results of randomized cross study |
| topic | chronic cardiac insufficiency torasemide furosemide |
| url | https://www.med-sovet.pro/jour/article/view/1367 |
| work_keys_str_mv | AT eeaverin torasemidesafetyincomplextherapyofchroniccardiacinsufficiencyresultsofrandomizedcrossstudy |