Cryo-electron Microscopy Structure of the <named-content content-type="genus-species">Acinetobacter baumannii</named-content> 70S Ribosome and Implications for New Antibiotic Development

Cryo-electron Microscopy Structure of the <named-content content-type="genus-species">Acinetobacter baumannii</named-content> 70S Ribosome and Implications for New Antibiotic Development

ABSTRACT Antimicrobial resistance is a major health threat as it limits treatment options for infection. At the forefront of this serious issue is Acinetobacter baumannii, a Gram-negative opportunistic pathogen that exhibits the remarkable ability to resist antibiotics through multiple mechanisms. A...

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Bibliographic Details
Main Authors: Christopher E. Morgan, Wei Huang, Susan D. Rudin, Derek J. Taylor, James E. Kirby, Robert A. Bonomo, Edward W. Yu
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mBio
Subjects:
70S ribosome
Acinetobacter baumannii
cryo-EM
antibiotic resistance
structural biology
Online Access:https://journals.asm.org/doi/10.1128/mBio.03117-19

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