A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial
OBJECTIVES: Negative-pressure wound therapy has been widely adopted to reduce the complexity of treating a broad range of acute and chronic wounds. However, its cost is high. The objective of this study was to evaluate the following two different methods of negative-pressure wound therapy in terms o...
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| Format: | Article |
| Language: | English |
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Elsevier España
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| Series: | Clinics |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017001200737&lng=en&tlng=en |
| _version_ | 1811228859280916480 |
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| author | Fabio Kamamoto Ana Lucia Munhoz Lima Marcelo Rosa de Rezende Rames Mattar-Junior Marcos de Camargo Leonhardt Kodi Edson Kojima Carla Chineze dos Santos |
| author_facet | Fabio Kamamoto Ana Lucia Munhoz Lima Marcelo Rosa de Rezende Rames Mattar-Junior Marcos de Camargo Leonhardt Kodi Edson Kojima Carla Chineze dos Santos |
| author_sort | Fabio Kamamoto |
| collection | DOAJ |
| description | OBJECTIVES: Negative-pressure wound therapy has been widely adopted to reduce the complexity of treating a broad range of acute and chronic wounds. However, its cost is high. The objective of this study was to evaluate the following two different methods of negative-pressure wound therapy in terms of healing time: a low-cost method of negative-pressure wound therapy (a pressure stabilizer device connected to a hospital wall-vacuum system with a gauze-sealed dressing, USP) and the standard of care (vacuum-assisted closure, VAC). METHODS: This is a randomized, controlled, non-inferiority, unblinded trial. Patients admitted with complex injuries to a trauma center in a public referral hospital who were indicated for orthopedic surgery were randomized to a USP or VAC group. The primary outcome was the time required to achieve a “ready for surgery condition”, which was defined as a wound bed with healthy granulation tissue and without necrosis or purulent secretion. Wound bed area contraction, granulation tissue growth and the direct costs of the dressings were secondary outcomes. RESULTS: Variation in area and granulation tissue growth were essentially the same between the systems, and healing time was equal between the groups (p=0.379). In both systems, serial debridement increased wound area (p=0.934), and granulation tissue was also increased (p=0.408). The mean treatment cost was US$ 15.15 in the USP group and US$ 872.59 in the VAC group. CONCLUSIONS: For treating complex traumatic injuries, USP was non-inferior to and less expensive than VAC. |
| first_indexed | 2024-04-12T10:03:24Z |
| format | Article |
| id | doaj.art-9abdbac193924357ac5a7b0a83b3cad5 |
| institution | Directory Open Access Journal |
| issn | 1980-5322 |
| language | English |
| last_indexed | 2024-04-12T10:03:24Z |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-9abdbac193924357ac5a7b0a83b3cad52022-12-22T03:37:30ZengElsevier EspañaClinics1980-5322721273774210.6061/clinics/2017(12)04S1807-59322017001200737A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trialFabio KamamotoAna Lucia Munhoz LimaMarcelo Rosa de RezendeRames Mattar-JuniorMarcos de Camargo LeonhardtKodi Edson KojimaCarla Chineze dos SantosOBJECTIVES: Negative-pressure wound therapy has been widely adopted to reduce the complexity of treating a broad range of acute and chronic wounds. However, its cost is high. The objective of this study was to evaluate the following two different methods of negative-pressure wound therapy in terms of healing time: a low-cost method of negative-pressure wound therapy (a pressure stabilizer device connected to a hospital wall-vacuum system with a gauze-sealed dressing, USP) and the standard of care (vacuum-assisted closure, VAC). METHODS: This is a randomized, controlled, non-inferiority, unblinded trial. Patients admitted with complex injuries to a trauma center in a public referral hospital who were indicated for orthopedic surgery were randomized to a USP or VAC group. The primary outcome was the time required to achieve a “ready for surgery condition”, which was defined as a wound bed with healthy granulation tissue and without necrosis or purulent secretion. Wound bed area contraction, granulation tissue growth and the direct costs of the dressings were secondary outcomes. RESULTS: Variation in area and granulation tissue growth were essentially the same between the systems, and healing time was equal between the groups (p=0.379). In both systems, serial debridement increased wound area (p=0.934), and granulation tissue was also increased (p=0.408). The mean treatment cost was US$ 15.15 in the USP group and US$ 872.59 in the VAC group. CONCLUSIONS: For treating complex traumatic injuries, USP was non-inferior to and less expensive than VAC.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017001200737&lng=en&tlng=enNegative-Pressure Wound TherapyWound HealingWounds and InjuriesCost Savings |
| spellingShingle | Fabio Kamamoto Ana Lucia Munhoz Lima Marcelo Rosa de Rezende Rames Mattar-Junior Marcos de Camargo Leonhardt Kodi Edson Kojima Carla Chineze dos Santos A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial Clinics Negative-Pressure Wound Therapy Wound Healing Wounds and Injuries Cost Savings |
| title | A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial |
| title_full | A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial |
| title_fullStr | A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial |
| title_full_unstemmed | A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial |
| title_short | A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial |
| title_sort | new low cost negative pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries a prospective randomized non inferiority trial |
| topic | Negative-Pressure Wound Therapy Wound Healing Wounds and Injuries Cost Savings |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017001200737&lng=en&tlng=en |
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