Purine metabolism-related gene expression signature predicts survival outcome and indicates immune microenvironment profile of gliomas

Glioma is the most common malignant tumor in the central nervous system. The impact of metabolism on cancer development and the immune microenvironment landscape has recently gained broad attention. Purines are involved in multiple metabolic pathways. It has been proved that purine metabolism could...

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Bibliographic Details
Main Authors:	Siliang Chen, Shuxin Zhang, Zhihao Wang, Junhong Li, Yunbo Yuan, Tengfei Li, Mingrong Zuo, Wentao Feng, Wenhao Li, Mina Chen, Yanhui Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Pharmacology
Subjects:	purine metabolism glioma tumor microenvironment prognosis immune infiltration immune checkpoint inhibitor
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1038272/full

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