STAT3 pathway is involved in interleukin-22 promoting expression of tight junction protein in human colorectal cancer cell line HT29

STAT3 pathway is involved in interleukin-22 promoting expression of tight junction protein in human colorectal cancer cell line HT29

Objective To investigate the effect of interleukin-22(IL-22) on intestinal epithelial barrier tight junction and its mechanism. Methods Human colon cancer HT29 cells were divided into control group, IL-22 group(100 ng/mL), FLLL32 group(pretreatment with FLLL32 before IL-22 intervention) and colive...

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Bibliographic Details
Main Author:	SONG Qian, HUANG Xue, QIN Meng-bin, ZHANG Jun-hong, JING Jie, LUO Yi-hua, LI Yu-xin
Format:	Article
Language:	zho
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2021-06-01
Series:	Jichu yixue yu linchuang
Subjects:	tight junction protein\|il-22\|stat3\|ulcerative colitis\|intestinal epithelial barrier
Online Access:	http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a210017.pdf

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