Characterization of sialylation-related long noncoding RNAs to develop a novel signature for predicting prognosis, immune landscape, and chemotherapy response in colorectal cancer

Characterization of sialylation-related long noncoding RNAs to develop a novel signature for predicting prognosis, immune landscape, and chemotherapy response in colorectal cancer

Aberrant sialylation plays a key biological role in tumorigenesis and metastasis, including tumor cell survival and invasion, immune evasion, angiogenesis, and resistance to therapy. It has been proposed as a possible cancer biomarker and a potential therapeutic target of tumors. Nevertheless, the p...

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Bibliographic Details
Main Authors: Mingxuan Zhou, Silin Lv, Yufang Hou, Rixin Zhang, Weiqi Wang, Zheng Yan, Tiegang Li, Wenqiang Gan, Zifan Zeng, Fang Zhang, Min Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
sialylation
long noncoding RNA
colorectal cancer
prognostic signature
immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.994874/full

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