TRPML1—Emerging Roles in Cancer

TRPML1—Emerging Roles in Cancer

The mucolipin-1 (TRPML1) channel maintains lysosomal ionic homeostasis and regulates autophagic flux. Defects of TRPML1 lead to lysosomal storage diseases and neurodegeneration. In this report, we discuss emerging evidence pertaining to differential regulation of TRPML1 signaling pathways in cancer...

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Bibliographic Details
Main Authors: Yiming Yang, Xingjian Zhai, Yassine El Hiani
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
cancer
lysosomes
TRPML1
mitochondria
Online Access:https://www.mdpi.com/2073-4409/9/12/2682

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