Dietary restriction in cerebral bioenergetics and redox state
The brain has a central role in the regulation of energy stability of the organism. It is the organ with the highest energetic demands, the most susceptible to energy deficits, and is responsible for coordinating behavioral and physiological responses related to food foraging and intake. Dietary int...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-01-01
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| Series: | Redox Biology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231714000044 |
| _version_ | 1811293537573011456 |
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| author | Ignacio Amigo Alicia J. Kowaltowski |
| author_facet | Ignacio Amigo Alicia J. Kowaltowski |
| author_sort | Ignacio Amigo |
| collection | DOAJ |
| description | The brain has a central role in the regulation of energy stability of the organism. It is the organ with the highest energetic demands, the most susceptible to energy deficits, and is responsible for coordinating behavioral and physiological responses related to food foraging and intake. Dietary interventions have been shown to be a very effective means to extend lifespan and delay the appearance of age-related pathological conditions, notably those associated with brain functional decline. The present review focuses on the effects of these interventions on brain metabolism and cerebral redox state, and summarizes the current literature dealing with dietary interventions on brain pathology. |
| first_indexed | 2024-04-13T05:02:51Z |
| format | Article |
| id | doaj.art-9ac9f400c2154166a3d4fecdc9f6b90f |
| institution | Directory Open Access Journal |
| issn | 2213-2317 |
| language | English |
| last_indexed | 2024-04-13T05:02:51Z |
| publishDate | 2014-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Redox Biology |
| spelling | doaj.art-9ac9f400c2154166a3d4fecdc9f6b90f2022-12-22T03:01:17ZengElsevierRedox Biology2213-23172014-01-012C29630410.1016/j.redox.2013.12.021Dietary restriction in cerebral bioenergetics and redox stateIgnacio AmigoAlicia J. KowaltowskiThe brain has a central role in the regulation of energy stability of the organism. It is the organ with the highest energetic demands, the most susceptible to energy deficits, and is responsible for coordinating behavioral and physiological responses related to food foraging and intake. Dietary interventions have been shown to be a very effective means to extend lifespan and delay the appearance of age-related pathological conditions, notably those associated with brain functional decline. The present review focuses on the effects of these interventions on brain metabolism and cerebral redox state, and summarizes the current literature dealing with dietary interventions on brain pathology.http://www.sciencedirect.com/science/article/pii/S2213231714000044Caloric restrictionNeurological diseasesMitochondriaEnergy metabolism |
| spellingShingle | Ignacio Amigo Alicia J. Kowaltowski Dietary restriction in cerebral bioenergetics and redox state Redox Biology Caloric restriction Neurological diseases Mitochondria Energy metabolism |
| title | Dietary restriction in cerebral bioenergetics and redox state |
| title_full | Dietary restriction in cerebral bioenergetics and redox state |
| title_fullStr | Dietary restriction in cerebral bioenergetics and redox state |
| title_full_unstemmed | Dietary restriction in cerebral bioenergetics and redox state |
| title_short | Dietary restriction in cerebral bioenergetics and redox state |
| title_sort | dietary restriction in cerebral bioenergetics and redox state |
| topic | Caloric restriction Neurological diseases Mitochondria Energy metabolism |
| url | http://www.sciencedirect.com/science/article/pii/S2213231714000044 |
| work_keys_str_mv | AT ignacioamigo dietaryrestrictionincerebralbioenergeticsandredoxstate AT aliciajkowaltowski dietaryrestrictionincerebralbioenergeticsandredoxstate |