Advances in the Research and Application of Smart-Responsive Hydrogels in Disease Treatment

Smart-responsive hydrogels have been widely used in various fields, particularly in the biomedical field. Compared with traditional hydrogels, smart-responsive hydrogels not only facilitate the encapsulation and controlled release of drugs, active substances, and even cells but, more importantly, th...

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Main Authors: Juan Cao, Ping Yuan, Bo Wu, Yeqi Liu, Cheng Hu
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/9/8/662
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author Juan Cao
Ping Yuan
Bo Wu
Yeqi Liu
Cheng Hu
author_facet Juan Cao
Ping Yuan
Bo Wu
Yeqi Liu
Cheng Hu
author_sort Juan Cao
collection DOAJ
description Smart-responsive hydrogels have been widely used in various fields, particularly in the biomedical field. Compared with traditional hydrogels, smart-responsive hydrogels not only facilitate the encapsulation and controlled release of drugs, active substances, and even cells but, more importantly, they enable the on-demand and controllable release of drugs and active substances at the disease site, significantly enhancing the efficacy of disease treatment. With the rapid advancement of biomaterials, smart-responsive hydrogels have received widespread attention, and a wide variety of smart-responsive hydrogels have been developed for the treatment of different diseases, thus presenting tremendous research prospects. This review summarizes the latest advancements in various smart-responsive hydrogels used for disease treatment. Additionally, some of the current shortcomings of smart-responsive hydrogels and the strategies to address them are discussed, as well as the future development directions and prospects of smart-responsive hydrogels.
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spelling doaj.art-9ad8d60c4d364017ab1854efc4c235072023-11-19T01:14:00ZengMDPI AGGels2310-28612023-08-019866210.3390/gels9080662Advances in the Research and Application of Smart-Responsive Hydrogels in Disease TreatmentJuan Cao0Ping Yuan1Bo Wu2Yeqi Liu3Cheng Hu4School of Fashion and Design Art, Sichuan Normal University, Chengdu 610066, ChinaSchool of Mechanical Engineering, Chengdu University, Chengdu 610106, ChinaSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, ChinaSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, ChinaNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610065, ChinaSmart-responsive hydrogels have been widely used in various fields, particularly in the biomedical field. Compared with traditional hydrogels, smart-responsive hydrogels not only facilitate the encapsulation and controlled release of drugs, active substances, and even cells but, more importantly, they enable the on-demand and controllable release of drugs and active substances at the disease site, significantly enhancing the efficacy of disease treatment. With the rapid advancement of biomaterials, smart-responsive hydrogels have received widespread attention, and a wide variety of smart-responsive hydrogels have been developed for the treatment of different diseases, thus presenting tremendous research prospects. This review summarizes the latest advancements in various smart-responsive hydrogels used for disease treatment. Additionally, some of the current shortcomings of smart-responsive hydrogels and the strategies to address them are discussed, as well as the future development directions and prospects of smart-responsive hydrogels.https://www.mdpi.com/2310-2861/9/8/662smart-responsivehydrogelbiomaterialsdisease treatment
spellingShingle Juan Cao
Ping Yuan
Bo Wu
Yeqi Liu
Cheng Hu
Advances in the Research and Application of Smart-Responsive Hydrogels in Disease Treatment
Gels
smart-responsive
hydrogel
biomaterials
disease treatment
title Advances in the Research and Application of Smart-Responsive Hydrogels in Disease Treatment
title_full Advances in the Research and Application of Smart-Responsive Hydrogels in Disease Treatment
title_fullStr Advances in the Research and Application of Smart-Responsive Hydrogels in Disease Treatment
title_full_unstemmed Advances in the Research and Application of Smart-Responsive Hydrogels in Disease Treatment
title_short Advances in the Research and Application of Smart-Responsive Hydrogels in Disease Treatment
title_sort advances in the research and application of smart responsive hydrogels in disease treatment
topic smart-responsive
hydrogel
biomaterials
disease treatment
url https://www.mdpi.com/2310-2861/9/8/662
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AT yeqiliu advancesintheresearchandapplicationofsmartresponsivehydrogelsindiseasetreatment
AT chenghu advancesintheresearchandapplicationofsmartresponsivehydrogelsindiseasetreatment