Effects of Lead Toxicity on Spermatogenesis in the Testes of Albino Rats
Objective: The objective of this study was to observe changes in spermatogenesis in the testes of albino rats exposed to lead acetate. Study Design: An experimental animals study Place of Study and Duration: This study was carried out in the Department of Anatomy, Islamic International Medical Colle...
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| Format: | Article |
| Language: | English |
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Riphah International University, Islamabad
2011-07-01
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| Series: | Journal of Islamic International Medical College |
| Subjects: | |
| Online Access: | https://journals.riphah.edu.pk/index.php/jiimc/article/view/796 |
| _version_ | 1797986392981110784 |
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| author | Dr. Saffia Shaukat, Dr. Shabana Ali, Dr. Fatima Riaz |
| author_facet | Dr. Saffia Shaukat, Dr. Shabana Ali, Dr. Fatima Riaz |
| author_sort | Dr. Saffia Shaukat, Dr. Shabana Ali, Dr. Fatima Riaz |
| collection | DOAJ |
| description | Objective: The objective of this study was to observe changes in spermatogenesis in the testes of albino rats exposed to lead acetate.
Study Design: An experimental animals study
Place of Study and Duration: This study was carried out in the Department of Anatomy, Islamic International Medical College Rawalpindi and at National Institute of Health Islamabad from January to April, 2009.
Materials and Methods: Male adult rats were exposed to lead acetate with intraperitoneal dose of 4mg/Kg body weight for 5 days a week for 6 weeks. The animals in groupAwere used as control. The animals of groups B were treated with lead acetate with specified dose for 6 weeks. After 6 weeks the animals of subgroup B were sacrificed. The results of these two groups were then compared.
Results: After six weeks, it was observed that the number of spermatogenic cells had decreased in the test groups as compared with control group (p<0.05).
Conclusion: Lead is toxic for cells of spermatogenic series, injurious to heaith and plays a significant role in reducing male fertility. |
| first_indexed | 2024-04-11T07:33:16Z |
| format | Article |
| id | doaj.art-9adf459fb3d24e418ca1dfd28b3dccdb |
| institution | Directory Open Access Journal |
| issn | 1815-4018 2410-5422 |
| language | English |
| last_indexed | 2024-04-11T07:33:16Z |
| publishDate | 2011-07-01 |
| publisher | Riphah International University, Islamabad |
| record_format | Article |
| series | Journal of Islamic International Medical College |
| spelling | doaj.art-9adf459fb3d24e418ca1dfd28b3dccdb2022-12-22T04:36:49ZengRiphah International University, IslamabadJournal of Islamic International Medical College1815-40182410-54222011-07-016133361192Effects of Lead Toxicity on Spermatogenesis in the Testes of Albino RatsDr. Saffia Shaukat, Dr. Shabana Ali, Dr. Fatima RiazObjective: The objective of this study was to observe changes in spermatogenesis in the testes of albino rats exposed to lead acetate. Study Design: An experimental animals study Place of Study and Duration: This study was carried out in the Department of Anatomy, Islamic International Medical College Rawalpindi and at National Institute of Health Islamabad from January to April, 2009. Materials and Methods: Male adult rats were exposed to lead acetate with intraperitoneal dose of 4mg/Kg body weight for 5 days a week for 6 weeks. The animals in groupAwere used as control. The animals of groups B were treated with lead acetate with specified dose for 6 weeks. After 6 weeks the animals of subgroup B were sacrificed. The results of these two groups were then compared. Results: After six weeks, it was observed that the number of spermatogenic cells had decreased in the test groups as compared with control group (p<0.05). Conclusion: Lead is toxic for cells of spermatogenic series, injurious to heaith and plays a significant role in reducing male fertility.https://journals.riphah.edu.pk/index.php/jiimc/article/view/796spermatogenesis, lead toxicity, rat fertility |
| spellingShingle | Dr. Saffia Shaukat, Dr. Shabana Ali, Dr. Fatima Riaz Effects of Lead Toxicity on Spermatogenesis in the Testes of Albino Rats Journal of Islamic International Medical College spermatogenesis, lead toxicity, rat fertility |
| title | Effects of Lead Toxicity on Spermatogenesis in the Testes of Albino Rats |
| title_full | Effects of Lead Toxicity on Spermatogenesis in the Testes of Albino Rats |
| title_fullStr | Effects of Lead Toxicity on Spermatogenesis in the Testes of Albino Rats |
| title_full_unstemmed | Effects of Lead Toxicity on Spermatogenesis in the Testes of Albino Rats |
| title_short | Effects of Lead Toxicity on Spermatogenesis in the Testes of Albino Rats |
| title_sort | effects of lead toxicity on spermatogenesis in the testes of albino rats |
| topic | spermatogenesis, lead toxicity, rat fertility |
| url | https://journals.riphah.edu.pk/index.php/jiimc/article/view/796 |
| work_keys_str_mv | AT drsaffiashaukatdrshabanaalidrfatimariaz effectsofleadtoxicityonspermatogenesisinthetestesofalbinorats |