Plasmonic Fluorescence Sensors in Diagnosis of Infectious Diseases
The increasing demand for rapid, cost-effective, and reliable diagnostic tools in personalized and point-of-care medicine is driving scientists to enhance existing technology platforms and develop new methods for detecting and measuring clinically significant biomarkers. Humanity is confronted with...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/14/3/130 |
| _version_ | 1827306905800802304 |
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| author | Juiena Hasan Sangho Bok |
| author_facet | Juiena Hasan Sangho Bok |
| author_sort | Juiena Hasan |
| collection | DOAJ |
| description | The increasing demand for rapid, cost-effective, and reliable diagnostic tools in personalized and point-of-care medicine is driving scientists to enhance existing technology platforms and develop new methods for detecting and measuring clinically significant biomarkers. Humanity is confronted with growing risks from emerging and recurring infectious diseases, including the influenza virus, dengue virus (DENV), human immunodeficiency virus (HIV), Ebola virus, tuberculosis, cholera, and, most notably, SARS coronavirus-2 (SARS-CoV-2; COVID-19), among others. Timely diagnosis of infections and effective disease control have always been of paramount importance. Plasmonic-based biosensing holds the potential to address the threat posed by infectious diseases by enabling prompt disease monitoring. In recent years, numerous plasmonic platforms have risen to the challenge of offering on-site strategies to complement traditional diagnostic methods like polymerase chain reaction (PCR) and enzyme-linked immunosorbent assays (ELISA). Disease detection can be accomplished through the utilization of diverse plasmonic phenomena, such as propagating surface plasmon resonance (SPR), localized SPR (LSPR), surface-enhanced Raman scattering (SERS), surface-enhanced fluorescence (SEF), surface-enhanced infrared absorption spectroscopy, and plasmonic fluorescence sensors. This review focuses on diagnostic methods employing plasmonic fluorescence sensors, highlighting their pivotal role in swift disease detection with remarkable sensitivity. It underscores the necessity for continued research to expand the scope and capabilities of plasmonic fluorescence sensors in the field of diagnostics. |
| first_indexed | 2024-04-24T18:30:21Z |
| format | Article |
| id | doaj.art-9ae1862e9d4844ac812a34c4c05bad75 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-04-24T18:30:21Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-9ae1862e9d4844ac812a34c4c05bad752024-03-27T13:28:12ZengMDPI AGBiosensors2079-63742024-03-0114313010.3390/bios14030130Plasmonic Fluorescence Sensors in Diagnosis of Infectious DiseasesJuiena Hasan0Sangho Bok1Department of Electrical and Computer Engineering, Ritchie School of Engineering and Computer Science, University of Denver, Denver, CO 80208, USADepartment of Electrical and Computer Engineering, Ritchie School of Engineering and Computer Science, University of Denver, Denver, CO 80208, USAThe increasing demand for rapid, cost-effective, and reliable diagnostic tools in personalized and point-of-care medicine is driving scientists to enhance existing technology platforms and develop new methods for detecting and measuring clinically significant biomarkers. Humanity is confronted with growing risks from emerging and recurring infectious diseases, including the influenza virus, dengue virus (DENV), human immunodeficiency virus (HIV), Ebola virus, tuberculosis, cholera, and, most notably, SARS coronavirus-2 (SARS-CoV-2; COVID-19), among others. Timely diagnosis of infections and effective disease control have always been of paramount importance. Plasmonic-based biosensing holds the potential to address the threat posed by infectious diseases by enabling prompt disease monitoring. In recent years, numerous plasmonic platforms have risen to the challenge of offering on-site strategies to complement traditional diagnostic methods like polymerase chain reaction (PCR) and enzyme-linked immunosorbent assays (ELISA). Disease detection can be accomplished through the utilization of diverse plasmonic phenomena, such as propagating surface plasmon resonance (SPR), localized SPR (LSPR), surface-enhanced Raman scattering (SERS), surface-enhanced fluorescence (SEF), surface-enhanced infrared absorption spectroscopy, and plasmonic fluorescence sensors. This review focuses on diagnostic methods employing plasmonic fluorescence sensors, highlighting their pivotal role in swift disease detection with remarkable sensitivity. It underscores the necessity for continued research to expand the scope and capabilities of plasmonic fluorescence sensors in the field of diagnostics.https://www.mdpi.com/2079-6374/14/3/130plasmonicsSPRLSPRinfectious diseasebiosensorsfluorescence |
| spellingShingle | Juiena Hasan Sangho Bok Plasmonic Fluorescence Sensors in Diagnosis of Infectious Diseases Biosensors plasmonics SPR LSPR infectious disease biosensors fluorescence |
| title | Plasmonic Fluorescence Sensors in Diagnosis of Infectious Diseases |
| title_full | Plasmonic Fluorescence Sensors in Diagnosis of Infectious Diseases |
| title_fullStr | Plasmonic Fluorescence Sensors in Diagnosis of Infectious Diseases |
| title_full_unstemmed | Plasmonic Fluorescence Sensors in Diagnosis of Infectious Diseases |
| title_short | Plasmonic Fluorescence Sensors in Diagnosis of Infectious Diseases |
| title_sort | plasmonic fluorescence sensors in diagnosis of infectious diseases |
| topic | plasmonics SPR LSPR infectious disease biosensors fluorescence |
| url | https://www.mdpi.com/2079-6374/14/3/130 |
| work_keys_str_mv | AT juienahasan plasmonicfluorescencesensorsindiagnosisofinfectiousdiseases AT sanghobok plasmonicfluorescencesensorsindiagnosisofinfectiousdiseases |