Protein Arginine Methyltransferase 5 Promotes Esophageal Squamous Cell Carcinoma Proliferation and Metastasis via LKB1/AMPK/mTOR Signaling Pathway

Protein Arginine Methyltransferase 5 Promotes Esophageal Squamous Cell Carcinoma Proliferation and Metastasis via LKB1/AMPK/mTOR Signaling Pathway

Background: Esophageal squamous cell carcinoma (ESCC) is the eighth most common cancer in the world. Protein arginine methyltransferase 5 (PRMT5), an enzyme that catalyzes symmetric and asymmetric methylation on arginine residues of histone and non-histone proteins, is overexpressed in many cancers....

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Bibliographic Details
Main Authors:	Yu-ru Chen, Hua-ni Li, Lian-jun Zhang, Chong Zhang, Jin-guang He
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-05-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	protein arginine methyltransferase 5 esophageal squamous cell carcinoma proliferation metastasis LKB1/AMPK/mTOR pathway signaling
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.645375/full

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