DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells.

DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells.

Pigs are proposed to be suitable large animal models for test of the efficacy and safety of induced pluripotent stem cells (iPSCs) for stem cell therapy, but authentic pig ES/iPS cell lines with germline competence are rarely produced. The pathways or signaling underlying the defective competent pig...

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Bibliographic Details
Main Authors: Kai Liu, Jian Mao, Lipu Song, Anran Fan, Sheng Zhang, Jianyu Wang, Nana Fan, Na Liu, Xiaoying Ye, Haifeng Fu, Zhongcheng Zhou, Yong Wang, Hong Wei, Zhonghua Liu, Ziyi Li, Liangxue Lai, Xumin Wang, Lin Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333863?pdf=render

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